Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.58 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | SCN10A | Q9Y5Y9 | 5/20 | 0.46 |
| ▸ | PIP4K2A | P48426 | 4/20 | 0.43 |
| ▸ | PIP4K2B | P78356 | 4/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | CCNC | P24863 | 3/20 | 0.42 |
| ▸ | CDK8 | P49336 | 3/20 | 0.42 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14495029 | 0.91 | CHRNA7 (0.52) | CHRNA7PDGFRAKDRSCN10APIP4K2A | |
| SCHEMBL5335824 | 0.85 | CHRNA7 (0.55) | CHRNA7SCN10AKCNH2SCN2ACCNC | |
| SCHEMBL5312257 | 0.84 | CHRNA7 (0.61) | CHRNA7PDGFRAKDRSCN10AKCNH2 | |
| SCHEMBL5313234 | 0.80 | CHRNA7 (0.49) | CHRNA7PDGFRAKDRSCN10ASCN2A | |
| SCHEMBL14573319 | 0.80 | CHRNA7 (0.70) | CHRNA7SCN10AKCNH2SCN2ACCNC | |
| SCHEMBL5315263 | 0.79 | CHRNA7 (0.69) | CHRNA7SCN10AKCNH2SCN2ACCNC | |
| SCHEMBL14494780 | 0.78 | CHRNA7 (0.59) | CHRNA7SCN10AKCNH2SCN2ACCNC | |
| SCHEMBL14494777 | 0.78 | CHRNA7 (0.55) | CHRNA7SCN10AKCNH2SCN2ACCNC | |
| SCHEMBL5313064 | 0.77 | CHRNA7 (0.66) | CHRNA7SCN10AKCNH2SCN2ACCNC | |
| SCHEMBL5317038 | 0.77 | BTK (0.57) | CHRNA7PDGFRAKDREPHB4BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007062459-A1 | SELECTIVE KINASE INHIBITORS BASED ON PYRIDINE SCAFFOLD | CYTOPIA RESEARCH PTY LTD (AU) | 2007-06-07 | — | — | WO | disclosed |