SCHEMBL5373230

SCHEMBL5373230

C=CC(=O)OC(CC)C(C)O

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.44
HPGD P15428 1/20 0.38
ALDH1A1 P00352 5/20 0.33
TP53 P04637 3/20 0.33
HIF1A Q16665 3/20 0.33
CYP3A4 P08684 2/20 0.33
HSD17B10 Q99714 1/20 0.33
THRB P10828 3/20 0.33
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2046277 0.86 TSHR (0.45) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL9720362 0.85 TSHR (0.41) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL23494343 0.84 TSHR (0.44) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27816092 0.84 TSHR (0.44) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27695890 0.84 TSHR (0.44) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL11023779 0.82 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL23494079 0.82 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL335610 0.81 TSHR (0.36) TSHRHPGDALDH1A1
SCHEMBL31190097 0.81 TSHR (0.37) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL23174693 0.81 TSHR (0.41) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110527326-A A kind of aeroge coating and preparation method thereof TANG XUEJIN 2019-12-03 CN disclosed
CN-109666319-A hard coating film and antireflection film 株式会社凸版巴川光学薄膜 2019-04-23 CN disclosed
CN-101453985-A Compositions for promoting hair growth NOVUS INT INC (US) 2009-06-10 CN disclosed
US-7253216-B2 Microencapsulating an anionically surface modified pigment by catalytic emulsion polymerization of a cationic polymerizable monomer; improved dispersion and ejection stability, colorfastness, print density, wear resistance, and image sharpness SEIKO EPSON CORPORATION (JP) 2007-08-07 US disclosed
US-20040229974-A1 Microencapsulating an anionically surface modified pigment by catalytic emulsion polymerization of a cationic polymerizable monomer; improved dispersion and ejection stability, colorfastness, print density, wear resistance, and image sharpness SEIKO EPSON CORPORATION 2004-11-18 US disclosed
CN-1175036-C Liquid curable resin composition DSM有限公司 2004-11-10 CN disclosed
CN-1260812-A Liquid curable resin composition DSM NV (NL) 2000-07-19 CN disclosed
US-4591610-A ONE CATIONIC POLYMER WITH ONE ANIONIC OR AMPHOTERIC POLYMER, XANTHAN GUM L'OREAL (FR) 1986-05-27 US disclosed