Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL465670 | 0.88 | TSHR (0.44) | TSHRHPGDTHRB | |
| SCHEMBL23494246 | 0.87 | TSHR (0.42) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL28391986 | 0.86 | TSHR (0.43) | TSHRHPGD | |
| SCHEMBL28195499 | 0.86 | TSHR (0.43) | TSHRHPGD | |
| SCHEMBL23174693 | 0.85 | TSHR (0.41) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL5373230 | 0.85 | TSHR (0.44) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL23493896 | 0.84 | TSHR (0.42) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL26841668 | 0.83 | TSHR (0.45) | TSHRHPGDTHRBALDH1A1TP53 | |
| Phosphoric Acid SCHEMBL21612159 | 0.82 | PTPN1 (0.40) | TSHRHPGDTHRB | |
| SCHEMBL1405779 | 0.82 | TSHR (0.47) | TSHRHPGDTHRBALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5095054-A | Molding premixes of a melt of a degraded starch and hydrophobic water-insoluble thermoplastic polymer; dimensional stability; toughness; humidity resistance; receptivity | WARNER-LAMBERT COMPANY (US) | 1992-03-10 | — | — | US | disclosed |