Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL537388 | 0.84 | TSHR (0.53) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL11964794 | 0.84 | TSHR (0.57) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL14173057 | 0.82 | TSHR (0.55) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL17489219 | 0.79 | TSHR (0.56) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL229378 | 0.79 | TSHR (0.66) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL18123454 | 0.77 | TSHR (0.63) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL19766702 | 0.77 | TSHR (0.49) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL11781129 | 0.77 | TSHR (0.57) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL536923 | 0.76 | TSHR (0.52) | TSHRALDH1A1THRB | |
| SCHEMBL8395663 | 0.76 | TSHR (0.61) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2941460-B1 | ONE -COMPONENT, CURABLE COATING COMPOSITION, PROCESSES FOR MAKING AND USING THEM, AND COATINGS AND ARTICLES PREPARED WITH THEM | BASF COATINGS GMBH (DE) | 2017-11-22 | — | — | EP | disclosed |
| US-9683125-B2 | One-component, curable coating compositions, processes for making and using them, and coatings and articles prepared with them | BASF COATINGS GMBH (DE) | 2017-06-20 | — | — | US | disclosed |
| US-20150337159-A1 | One-Component, Curable Coating Compositions, Processes For Making And Using Them, And Coatings And Articles Prepared With Them | BASF COATINGS GMBH (DE) | 2015-11-26 | — | — | US | disclosed |
| EP-2941460-A1 | ONE -COMPONENT, CURABLE COATING COMPOSITION, PROCESSES FOR MAKING AND USING THEM, AND COATINGS AND ARTICLES PREPARED WITH THEM | BASF Coatings GmbH (DE) | 2015-11-11 | — | — | EP | disclosed |
| US-8865851-B2 | Moisture-curing coating compositions comprising aprotic solvents and binders having alkoxysilane groups and method of forming a multicoat finish therewith | BASF COATINGS GMBH (DE) | 2014-10-21 | — | — | US | disclosed |
| WO-2014106552-A1 | ONE -COMPONENT, CURABLE COATING COMPOSITION, PROCESSES FOR MAKING AND USING THEM, AND COATINGS AND ARTICLES PREPARED WITH THEM | BASF COATINGS GMBH (DE) | 2014-07-10 | — | — | WO | disclosed |
| EP-2414466-B1 | MOISTURE-CURING COATING COMPOSITIONS BASED ON APROTIC SOLVENTS, COMPRISING BINDERS HAVING ALKOXYSILANE GROUPS, AND THE USE THEREOF | BASF COATINGS GMBH (DE) | 2013-10-16 | — | — | EP | disclosed |
| US-20120045586-A1 | MOISTURE-CURING COATING COMPOSITIONS BASED ON APROTIC SOLVENTS COMPRISING BINDERS HAVING ALKOXYSILANE GROUPS AND THE USE THEREOF | BASF COATINGS GMBH (DE) | 2012-02-23 | — | — | US | disclosed |
| EP-2414466-A1 | MOISTURE-CURING COATING COMPOSITIONS BASED ON APROTIC SOLVENTS, COMPRISING BINDERS HAVING ALKOXYSILANE GROUPS, AND THE USE THEREOF | BASF Coatings GmbH (DE) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010112106-A1 | MOISTURE-CURING COATING COMPOSITIONS BASED ON APROTIC SOLVENTS, COMPRISING BINDERS HAVING ALKOXYSILANE GROUPS, AND THE USE THEREOF | BASF COATINGS AG (DE) | 2010-10-07 | — | — | WO | disclosed |