Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21677119 | 1.00 | TSHR (0.61) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL12701633 | 0.89 | TSHR (0.67) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL25553220 | 0.87 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL8742010 | 0.85 | ATM (0.46) | TSHRHPGDALDH1A1ATMHCAR2 | |
| SCHEMBL29084605 | 0.85 | ATM (0.46) | TSHRHPGDALDH1A1ATMHCAR2 | |
| SCHEMBL22386407 | 0.84 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL4076455 | 0.82 | TSHR (0.59) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL25822500 | 0.82 | TSHR (0.64) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL25879296 | 0.82 | TSHR (0.63) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL74390 | 0.81 | TSHR (0.73) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915918-A1 | RESINS OF AMPHOTERIC ALDEHYDE POLYMERS AND USE OF SAID RESINS AS TEMPORARY WET-STRENGTH OR DRY-STRENGTH RESINS FOR PAPER | HERCULES INCORPORATED (US) | 1999-05-19 | — | — | EP | claimed |
| WO-1998054237-A1 | RESINS OF AMPHOTERIC ALDEHYDE POLYMERS AND USE OF SAID RESINS AS TEMPORARY WET-STRENGTH OR DRY-STRENGTH RESINS FOR PAPER | HERCULES INCORPORATED (US) | 1998-12-03 | — | — | WO | claimed |