Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL1924435 | 0.95 | — | — | |
| Bicarbonate SCHEMBL10962533 | 0.95 | CA4 (0.55) | — | |
| Bicarbonate SCHEMBL5079792 | 0.95 | — | — | |
| Bicarbonate SCHEMBL4097336 | 0.90 | CA4 (0.64) | — | |
| Bicarbonate SCHEMBL16893405 | 0.90 | — | — | |
| Bicarbonate SCHEMBL5068676 | 0.90 | — | — | |
| Bicarbonate SCHEMBL225640 | 0.90 | CA4 (0.50) | — | |
| Bicarbonate SCHEMBL4386959 | 0.90 | — | — | |
| Bicarbonate SCHEMBL22800564 | 0.90 | CA4 (0.50) | — | |
| Bicarbonate SCHEMBL6032220 | 0.90 | CA4 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104459129-A | Diagnostic kit for distinguishing active and latent mycobacterium tuberculosis infection | HUASHAN HOSPITAL FUDAN UNIV | 2015-03-25 | — | — | CN | claimed |
| JP-55134341-A | — | — | None | — | — | JP | disclosed |
| CN-109534365-A | A kind of circulation manufacturing method of sodium bicarbonate combined producting ammonium chloride | 刘松林 | 2019-03-29 | — | — | CN | disclosed |
| CN-108929332-A | IDO inhibitor | 南京明德新药研发股份有限公司 | 2018-12-04 | — | — | CN | disclosed |
| CN-104920880-B | A kind of feed and preparation method thereof fed without grass for beef cattle | 石家庄渴望饲料有限公司 | 2018-10-12 | — | — | CN | disclosed |
| CN-108294021-A | A kind of nicotine-matrine fumicants and preparation method thereof | 黑龙江省平山林业制药厂 | 2018-07-20 | — | — | CN | disclosed |
| CN-107934996-A | Process for producing baking soda and ammonium chloride by using triamine tail gas | 中昊(大连)化工研究设计院有限公司 | 2018-04-20 | — | — | CN | disclosed |
| EP-3160499-A1 | ANTIBODIES REACTIVE WITH AN EPITOPE LOCATED IN THE N-TERMINAL REGION OF MUC5AC COMPRISING CYSTEINE-RICH SUBDOMAIN 2 (CYS2) | Immunomedics, Inc. (US) | 2017-05-03 | — | — | EP | disclosed |
| US-20160347857-A1 | ANTIBODIES REACTIVE WITH AN EPITOPE LOCATED IN THE N-TERMINAL REGION OF MUC5AC COMPRISING CYSTEINE-RICH SUBDOMAIN 2 (CYS2) | IMMUNOMEDICS, INC. | 2016-12-01 | — | — | US | disclosed |
| US-9452228-B2 | Antibodies reactive with an epitope located in the N-terminal region of MUC5AC comprising cysteine-rich subdomain 2 (Cys2) | IMMUNOMEDICS, INC. (US) | 2016-09-27 | — | — | US | disclosed |
| CN-1058712-C | Microbicidal triazolyl derivatives | BAYER AG (DE) | 2000-11-22 | — | — | CN | disclosed |
| EP-1032575-A1 | 2,3-DIARYL-PYRAZOLO(1,5-B)PYRIDAZINES DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYCLOOXYGENASE 2 (COX-2) INHIBITORS | GLAXO GROUP LIMITED (GB) | 2000-09-06 | — | — | EP | disclosed |
| WO-2000026216-A1 | PYRAZOLOPYRIDINE DERIVATIVES AS SELECTIVE COX-2 INHIBITORS | GLAXO GROUP LIMITED (GB) | 2000-05-11 | — | — | WO | disclosed |
| WO-1999012930-A1 | 2,3-DIARYL-PYRAZOLO[1,5-B]PYRIDAZINES DERIVATIVES, THEIR PREPA RATION AND THEIR USE AS CYCLOOXYGENASE 2 (COX-2) INHIBITORS | GLAXO GROUP LIMITED (GB) | 1999-03-18 | — | — | WO | disclosed |
| CN-1174193-A | Microbicidal triazolyl derivative | BAYER AG (DE) | 1998-02-25 | — | — | CN | disclosed |
| CN-1164229-A | Microbicidal triazolyl derivatives | BAYER AG (DE) | 1997-11-05 | — | — | CN | disclosed |
| US-4328359-A | 15-Deoxy-16-substituted-19-chloro-20-nor-prostane derivatives of the E and F series | AMERICAN CYANAMID COMPANY (US) | 1982-05-04 | — | — | US | disclosed |
| US-4297516-A | PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1981-10-27 | — | — | US | disclosed |
| US-4278806-A | HYPOTENSIVE, ANTIINFLAMMATORY, ANTIULCER, BRONCHODILATOR, OXYTOCIC, FERTILITY, DECONGESTANT | AMERICAN CYANAMID COMPANY (US) | 1981-07-14 | — | — | US | disclosed |
| JP-S55134341-A | DEVICE FOR EXTRACTING SAMPLE FOR ANALYZING POWDER MATERIAL | TOYO SODA MFG CO LTD | 1980-10-20 | — | — | JP | disclosed |