Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 6/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL6032220 | 1.00 | CA4 (0.50) | CA4CA1CA2CA9FAHD1 | |
| Bicarbonate SCHEMBL3815650 | 0.95 | CA1 (0.56) | CA4CA1CA2CA9FAHD1 | |
| Bicarbonate SCHEMBL15428445 | 0.95 | CA1 (0.56) | CA4CA1CA2CA9FAHD1 | |
| Bicarbonate SCHEMBL8962302 | 0.95 | CA1 (0.56) | CA4CA1CA2CA9FAHD1 | |
| Bicarbonate SCHEMBL8862333 | 0.95 | CA1 (0.56) | CA4CA1CA2CA9FAHD1 | |
| Bicarbonate SCHEMBL10901890 | 0.95 | CA1 (0.56) | CA4CA1CA2CA9FAHD1 | |
| Bicarbonate SCHEMBL16568879 | 0.95 | CA1 (0.56) | CA4CA1CA2CA9FAHD1 | |
| Bicarbonate SCHEMBL8468228 | 0.95 | CA1 (0.56) | CA4CA1CA2CA9FAHD1 | |
| Bicarbonate SCHEMBL9247593 | 0.95 | CA1 (0.56) | CA4CA1CA2CA9FAHD1 | |
| Bicarbonate SCHEMBL10903415 | 0.95 | CA1 (0.56) | CA4CA1CA2CA9FAHD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116289295-B | Cotton-milk moisturizing soft towel and production process thereof | 江阴云智医疗无纺布制品有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-116289295-A | Cotton-milk moisturizing soft towel and production process thereof | 江阴云智医疗无纺布制品有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-219150122-U | Device for synchronously purifying, converting and pulping secondary use of sodium bicarbonate-ammonium bicarbonate-containing solution | 赣南科技学院 | 2023-06-09 | — | — | CN | claimed |
| CN-114921596-A | Production method of environment-friendly Italian style cowhide sofa leather | 河南中牛实业有限公司 | 2022-08-19 | — | — | CN | claimed |
| CN-114272935-A | Catalyst for catalyzing ammonia borane to produce hydrogen and preparation method thereof | 惠州学院 | 2022-04-05 | — | — | CN | claimed |
| CN-109836619-A | Oleic acid modified calcium carbonate | 湖南金箭新材料科技有限公司 | 2019-06-04 | — | — | CN | claimed |
| CN-108770902-A | Jujube wafer and processing method | 中玺（天津）枣业技术工程中心 | 2018-11-09 | — | — | CN | claimed |
| CN-108203762-A | Method for efficiently decomposing and leaching precious metal gold in waste circuit board | 南京工业大学 | 2018-06-26 | — | — | CN | claimed |
| US-12509552-B2 | Lipidated poly(amino acid) nanostructures | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2025-12-30 | — | — | US | disclosed |
| CN-119430231-A | Method and system for preparing sodium bicarbonate and co-producing ammonium sulfate from low-temperature mirabilite | 陕西航天机电环境工程设计院有限责任公司 | 2025-02-14 | — | — | CN | disclosed |
| US-11965889-B2 | Lysine monomethylated derivative and corresponding antibody and use thereof | PMT BIOLABS INC (CN) | 2024-04-23 | — | — | US | disclosed |
| CN-116289295-B | Cotton-milk moisturizing soft towel and production process thereof | 江阴云智医疗无纺布制品有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-114921596-B | Production method of environment-friendly Italian style cowhide sofa leather | 河南中牛实业有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-114956646-B | Method for improving internal curing efficiency of cement-based material SAP (super absorbent polymer) based on bicarbonate | 东南大学 | 2023-09-19 | — | — | CN | disclosed |
| US-5106665-A | Blend of polypropylene and lubricant | FUJI PHOTO FILM CO., LTD. (JP) | 1992-04-21 | — | — | US | disclosed |
| EP-0385199-A2 | Container for photographic film cartridge | FUJI PHOTO FILM CO., LTD. (JP) | 1990-09-05 | — | — | EP | disclosed |
| EP-0091973-B1 | CHLORINATED RUBBER AND POLYVINYL CHLORIDE COMPOSITION CONTAINING THE SAME | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1985-12-18 | — | — | EP | disclosed |
| US-4433105-A | CHLORINATED RUBBER IS BUTYLENE-ETHYLENE COPOLYMER OR BUTYLENE-ETHYLENE-5-ETHYLIDENE-2-NORBORNENE TERPOLYMER | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1984-02-21 | — | — | US | disclosed |
| EP-0091973-A1 | Chlorinated rubber and polyvinyl chloride composition containing the same | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1983-10-26 | — | — | EP | disclosed |
| US-3967045-A | Pre-coated metal sheet | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JA) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11965889-B2 | Lysine monomethylated derivative and corresponding antibody and use thereof | KMT5A, PTMS, KDM4D | CA4 1185/4885CA1 1619/4885CA2 3226/4885 |
| US-12509552-B2 | Lipidated poly(amino acid) nanostructures | LNPEP, SET, PLTP | CA4 4403/4885CA1 3756/4885CA2 3582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.