SCHEMBL5374093

SCHEMBL5374093

COc1cc(NC(=O)CC(C)=O)c(C)cc1S(=O)(=O)O

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.49
ALDH1A1 P00352 5/20 0.49
MEN1 O00255 4/20 0.49
SMN1; SMN2 Q16637 4/20 0.39
LMNA P02545 3/20 0.39
MAPT P10636 2/20 0.39
KDM4E B2RXH2 1/20 0.39
GAA P10253 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7804751 0.89 ALDH1A1 (0.55) KMT2AALDH1A1MEN1SMN1; SMN2MAPT
SCHEMBL11332127 0.84 MEN1 (0.42) KMT2AALDH1A1MEN1SMN1; SMN2LMNA
SCHEMBL7075714 0.84 ALDH1A1 (0.49) KMT2AALDH1A1MEN1SMN1; SMN2MAPT
SCHEMBL389605 0.84 ALDH1A1 (0.52) KMT2AALDH1A1MEN1SMN1; SMN2LMNA
SCHEMBL29466718 0.84 ALDH1A1 (0.52) KMT2AALDH1A1MEN1SMN1; SMN2LMNA
SCHEMBL11331312 0.83 ALDH1A1 (0.55) KMT2AALDH1A1MEN1SMN1; SMN2MAPT
SCHEMBL2911518 0.83 ALDH1A1 (0.60) KMT2AALDH1A1MEN1SMN1; SMN2LMNA
Ammonia Solution, Strong SCHEMBL10606731 0.83 ALDH1A1 (0.51) KMT2AALDH1A1MEN1SMN1; SMN2LMNA
Ammonia Solution, Strong SCHEMBL10606720 0.83 ALDH1A1 (0.51) KMT2AALDH1A1MEN1SMN1; SMN2LMNA
SCHEMBL27548350 0.81 CA1 (0.46) KMT2AALDH1A1MEN1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6548647-B2 Spraying coupling components in solution or suspension to collide in reactor chamber, then pressurizing to remove; useful for offset printing inks CLARIANT GMBH (DE) 2003-04-15 US claimed
US-20020055619-A1 Process for preparing azo colorants CLARIANT GMBH 2002-05-09 US claimed
EP-1195411-A1 Process for the preparation of azo colourants Clariant GmbH (DE) 2002-04-10 EP claimed
US-7309389-B2 Preparation of azo colorants in microreactors and their use in electrophotographic toners and developers, powder coatings, ink jet inks and electronic medias CLARIANT FINANCE (BVI) LIMITED (VG) 2007-12-18 US disclosed
US-7135266-B2 Preparation of azo colorants in microreactors and their use in electrophotographic toners and developers, powder coatings, ink jet inks and electronic medias CLARIANT FINANCE (BVI) LIMITED (VG) 2006-11-14 US disclosed
US-20060228640-A1 Preparation of azo colorants in microreactors and their use in electrophotographic toners and developers, powder coatings, ink jet inks and electronic medias CLARIANT FINANCE (BVI) LIMITED 2006-10-12 US disclosed
US-20060042117-A1 Method and device for carrying out chemical and physical methods CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2006-03-02 US disclosed
EP-1558682-A1 METHOD AND DEVICE FOR CARRYING OUT CHEMICAL AND PHYSICAL METHODS Clariant GmbH (DE) 2005-08-03 EP disclosed
EP-1363975-B1 METHOD AND DEVICE FOR CONTINUOUS REDOX ADJUSTMENT IN AZOIC COUPLINGS CLARANT GMBH (DE) 2005-03-30 EP disclosed
US-20040131507-A1 Adjustment of concentration of reactants; rotating electrodes transverse to fluid flow; process control SAITMACHER KLAUS (DE) 2004-07-08 US disclosed
WO-2004037929-A1 METHOD AND DEVICE FOR CARRYING OUT CHEMICAL AND PHYSICAL METHODS CLARIANT GMBH (DE) 2004-05-06 WO disclosed
EP-1257602-B1 METHOD FOR PRODUCTION OF AZO DYES IN MICROREACTORS CLARIANT INT LTD (CH) 2003-11-12 EP disclosed
US-20030083410-A1 Preparation of azo colorants in microreactors and their use in electrophotographic toners and developers, powder coatings, ink jet inks and electronic medias CLARIANT FINANCE ( BVI) LIMITED 2003-05-01 US disclosed
US-6548647-B2 Spraying coupling components in solution or suspension to collide in reactor chamber, then pressurizing to remove; useful for offset printing inks CLARIANT GMBH (DE) 2003-04-15 US disclosed
EP-1257602-A1 METHOD FOR PRODUCTION OF AZO DYES IN MICROREACTORS CLARIANT INTERNATIONAL LTD. (CH) 2002-11-20 EP disclosed
US-6469147-B2 DIAZOTIZATION CLARIANT FINANCE (BVI) LIMITED (VG) 2002-10-22 US disclosed
US-20020055619-A1 Process for preparing azo colorants CLARIANT GMBH 2002-05-09 US disclosed
EP-1195411-A1 Process for the preparation of azo colourants Clariant GmbH (DE) 2002-04-10 EP disclosed
US-20010029294-A1 Preparation of azo colorants in microreactors CLARIANT INTERNATIONAL LTD. 2001-10-11 US disclosed
WO-2001059013-A1 METHOD FOR PRODUCTION OF AZO DYES IN MICROREACTORS CLARIANT INTERNATIONAL LTD (CH) 2001-08-16 WO disclosed