Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.58 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.54 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.54 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.54 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.54 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 5/20 | 0.51 |
| ▸ | BCHE | P06276 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4621517 | 1.00 | CCR3 (0.58) | CCR3PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL5969011 | 1.00 | CCR3 (0.58) | CCR3PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL15045173 | 0.91 | CCR3 (0.55) | CCR3PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL7514732 | 0.91 | CYP2D6 (0.59) | CCR3ACHEBCHEALDH1A1CYP1A2 | |
| SCHEMBL544141 | 0.90 | CCR3 (0.67) | CCR3PRMT3CARM1PRMT6PRMT1 | |
| Hydrochloric Acid SCHEMBL6092095 | 0.89 | CCR3 (0.65) | CCR3PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL3074896 | 0.87 | CCR3 (0.62) | CCR3PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL242758 | 0.87 | CCR3 (0.62) | CCR3PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL1180490 | 0.87 | CCR3 (0.62) | CCR3PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL12513916 | 0.84 | CCR3 (0.58) | CCR3ACHEBCHEALDH1A1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414368-A2 | HYDROXYTHIENOQUINOLONES AND RELATED COMPOUNDS AS ANTI-INFECTIVE AGENTS | Achillion Pharmaceuticals, Inc. (US) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010115184-A2 | HYDROXYTHIENOQUINOLONES AND RELATED COMPOUNDS AS ANTI-INFECTIVE AGENTS | ACHILLION PHARMACEUTICALS, INC. (US) | 2010-10-07 | — | — | WO | disclosed |