SCHEMBL544141

SCHEMBL544141

NCCC1CCN(Cc2ccccc2)CC1

nearest known ligand 0.67

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ CCR3 P51677 1/20 0.67
▸ ACHE P22303 8/20 0.60
▸ BCHE P06276 2/20 0.60
▸ ALDH1A1 P00352 1/20 0.58
▸ CXCR4 P61073 1/20 0.58
▸ PRMT3 O60678 1/20 0.57
▸ CARM1 Q86X55 1/20 0.57
▸ PRMT6 Q96LA8 1/20 0.57
▸ PRMT1 Q99873 1/20 0.57
▸ PRMT8 Q9NR22 1/20 0.57
▸ SIGMAR1 Q99720 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6092095 0.98 CCR3 (0.65) CCR3ACHEBCHEALDH1A1CXCR4
SCHEMBL5969011 0.90 CCR3 (0.58) CCR3ACHEBCHEALDH1A1CXCR4
SCHEMBL537415 0.90 CCR3 (0.58) CCR3ACHEBCHEALDH1A1CXCR4
SCHEMBL4621517 0.90 CCR3 (0.58) CCR3ACHEBCHEALDH1A1CXCR4
SCHEMBL8825330 0.90 CCR3 (0.63) CCR3ACHEBCHEALDH1A1CXCR4
SCHEMBL7272428 0.89 CCR3 (0.61) CCR3ACHEBCHEALDH1A1CXCR4
SCHEMBL15140944 0.87 CCR3 (0.73) CCR3ACHEBCHEALDH1A1CXCR4
SCHEMBL3107807 0.86 CCR3 (0.71) CCR3ACHEBCHEALDH1A1CXCR4
SCHEMBL1061878 0.86 CCR3 (0.71) CCR3ACHEBCHEALDH1A1CXCR4
SCHEMBL15933900 0.85 MAPT (0.68) ACHEALDH1A1CXCR4SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9737875-B2 Affinity reagents for protein purification IMPOSSIBLE FOODS INC. (US) 2017-08-22 — — US claimed
CN-104620104-B Affinity Reagents for Protein Purification 非凡食品有限公司 2017-03-01 — — CN claimed
US-7462613-B2 Pyridazinone derivatives as pharmaceuticals and pharmaceutical compositions containing them SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2008-12-09 — — US claimed
US-20060122229-A1 4,5-diarylthiazole derivatives as cb-1 ligands ASTRAZENECA AB (SE) 2006-06-08 — — US claimed
CN-1753672-A 4,5-diarylthiazole derivatives as cb-1 ligands ASTRAZENECA AB (SE) 2006-03-29 — — CN claimed
EP-1581214-A1 4,5-DIARYLTHIAZOLE DERIVATIVES AS CB-1 LIGANDS Astrazeneca AB (SE) 2005-10-05 — — EP claimed
WO-2004058255-A1 4, 5-DIARYLTHIAZOLE DERIVATIVES AS CB-1 LIGANDS ASTRAZENECA AB (SE) 2004-07-15 — — WO claimed
EP-0385044-A1 New piperidine derivatives as antihistaminics FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (FAES) (ES) 1990-09-05 — — EP claimed
CN-116283769-B Cyclobutane combination pyridine sulfonamide compound 绍兴市上虞区武汉理工大学高等研究院 2025-03-25 — — CN disclosed
WO-2025022031-A1 NEW DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) 2025-01-30 — — WO disclosed
WO-2024026026-A1 HIGH THROUGHPUT IN VIVO SCREENING OF LIPID NANOPARTICLES TRUSTEES OF TUFTS COLLEGE (US) 2024-02-01 — — WO disclosed
US-20230234917-A1 ASPARAGINE DERIVATIVES AND METHODS OF USING SAME SENDA BIOSCIENCES INC (US) 2023-07-27 — — US disclosed
US-20230234917-A1 ASPARAGINE DERIVATIVES AND METHODS OF USING SAME SENDA BIOSCIENCES INC (US) 2023-07-27 — — US disclosed
CN-116283769-A Cyclobutane-pyridine sulfonamide compound 绍兴市上虞区武汉理工大学高等研究院 2023-06-23 — — CN disclosed
US-4849431-A ANTICHOLINESTERASE ACTIVITY EISAI CO., LTD. (JP) 1989-07-18 — — US disclosed
CN-1030752-A Preparation method of cyclic amine compound EISAI CO LTD (JP) 1989-02-01 — — CN disclosed
EP-0296560-A2 1,4-Substituted piperidines as acetylcholinesterase inhibitors and their use for the treatment of Alzheimer's disease Eisai Co., Ltd. (JP) 1988-12-28 — — EP disclosed
US-4709010-A TREATING OR PREVENTING HYPERTENSION OR HYPERALDESTERONISM MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1987-11-24 — — US disclosed
EP-0229391-A1 Piperidine derivate, its use and pharmaceutical composition containing it Eisai Co., Ltd. (JP) 1987-07-22 — — EP disclosed
EP-0179352-A2 Peptides MERCK PATENT GmbH (DE) 1986-04-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060122229-A1 4,5-diarylthiazole derivatives as cb-1 ligands CNR1, CNR2, NPY4R CCR3 688/4885ACHE 2463/4885BCHE 940/4885
US-20230234917-A1 ASPARAGINE DERIVATIVES AND METHODS OF USING SAME ASNS, SI, NARS1 CCR3 4321/4885ACHE 1493/4885BCHE 1281/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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