Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMBR | P28336 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | CTSB | P07858 | 1/20 | 0.60 |
| ▸ | CTSK | P43235 | 1/20 | 0.60 |
| ▸ | ERAP2 | Q6P179 | 5/20 | 0.59 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.59 |
| ▸ | IL1RN | P18510 | 3/20 | 0.59 |
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | MMP8 | P22894 | 1/20 | 0.59 |
| ▸ | MMP14 | P50281 | 1/20 | 0.59 |
| ▸ | TACR1 | P25103 | 1/20 | 0.57 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5383425 | 0.95 | NMBR (0.67) | NMBRMAPTLMNASIRT5GAA | |
| SCHEMBL5380441 | 0.92 | NMBR (0.74) | NMBRMAPTLMNASIRT5GAA | |
| SCHEMBL14595064 | 0.92 | NMBR (0.74) | NMBRMAPTLMNASIRT5GAA | |
| SCHEMBL5380023 | 0.90 | NMBR (0.71) | NMBRMAPTLMNASIRT5GAA | |
| SCHEMBL16617130 | 0.90 | NMBR (0.71) | NMBRMAPTLMNASIRT5GAA | |
| SCHEMBL11765479 | 0.90 | NMBR (0.71) | NMBRMAPTLMNASIRT5GAA | |
| SCHEMBL14027229 | 0.90 | NMBR (0.71) | NMBRMAPTLMNASIRT5GAA | |
| SCHEMBL1318661 | 0.90 | NMBR (0.73) | NMBRMAPTLMNAGAAHTT | |
| SCHEMBL29401413 | 0.90 | NMBR (0.73) | NMBRMAPTLMNAGAAHTT | |
| SCHEMBL17319524 | 0.90 | NMBR (0.73) | NMBRMAPTLMNAGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7163671-B2 | Long-term stabilized formulations | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2007-01-16 | — | — | US | disclosed |
| US-20030092622-A1 | Preparation stabilized over long time | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-05-15 | — | — | US | disclosed |
| EP-1260230-A1 | PREPARATIONS STABILIZED OVER LONG TIME | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-11-27 | — | — | EP | disclosed |