Toluene

Toluene

SCHEMBL5374477

[2H]C([2H])([2H])c1ccccc1

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL3837745 0.79
Toluene SCHEMBL29946194 0.79
Toluene SCHEMBL28236970 0.77
M-Xylene SCHEMBL18687164 0.76
P-Xylene SCHEMBL16530254 0.74
SCHEMBL12344964 0.72 ACHE (1.00)
Toluene SCHEMBL1 0.72
SCHEMBL12344943 0.72 ACHE (1.00)
Toluene SCHEMBL4429042 0.72 ACHE (1.00)
Toluene SCHEMBL175861 0.72 ACHE (1.00)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4741383-A1 COMPOUND AND USE THEREOF AS ANTI-CANCER DRUG Tyligand Bioscience (Shanghai) Limited (CN) 2026-05-13 EP disclosed
US-11795315-B2 Group 5 metal complexes for producing amine-functionalized polyolefins THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2023-10-24 US disclosed
CN-116715562-A Method for preparing benzyl deuterated chemical by photocatalysis and deuterated chemical 中国科学技术大学苏州高等研究院 2023-09-08 CN disclosed
CN-113905785-A Cystic fibrosis transmembrane conductance regulator modulators 弗特克斯药品有限公司 2022-01-07 CN disclosed
US-7307091-B2 Deuterated 3-piperidinopropiophenone and medicaments containing said compounds BDD BEROLINA DRUG DEVELOPMENT GMBH (DE) 2007-12-11 US disclosed
EP-1383752-B1 DEUTERATED 3-PIPERIDINOPROPIOPHENONE AND MEDICAMENTS CONTAINING SAID COMPOUNDS TURICUM DRUG DEV AG (CH) 2005-06-22 EP disclosed
US-20040186136-A1 Deuterated 3-piperidinopropiophenone and medicaments containing said compounds BDD BEROLINA DRUG DEVELOPMENT GMBH (DE) 2004-09-23 US disclosed
EP-1383752-A2 DEUTERATED 3-PIPERIDINOPROPIOPHENONE AND MEDICAMENTS CONTAINING SAID COMPOUNDS Turicum Drug Development AG (CH) 2004-01-28 EP disclosed
WO-2002088100-A2 DEUTERATED 3-PIPERIDINOPROPIOPHENONE AND MEDICAMENTS CONTAINING SAID COMPOUNDS TURICUM DRUG DEVELOPMENT AG (CH) 2002-11-07 WO disclosed