Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL28264291 | 1.00 | TSHR (0.63) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL28904623 | 0.95 | TSHR (0.63) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL27501109 | 0.92 | TSHR (0.67) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL28124478 | 0.92 | TSHR (0.75) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL319125 | 0.92 | TSHR (0.75) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL28067703 | 0.92 | TSHR (0.75) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL252928 | 0.92 | TSHR (0.75) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Benzoic Acid SCHEMBL3958335 | 0.90 | TSHR (0.67) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL29173182 | 0.89 | TSHR (0.71) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL28496066 | 0.89 | TSHR (0.71) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110317435-B | Multifunctional cold-resistant low-odor composite material and preparation method thereof | 上海金发科技发展有限公司 | 2021-09-17 | — | — | CN | claimed |
| CN-111751916-A | Barrier layer film structure and application thereof | 宁波瑞凌新能源科技有限公司 | 2020-10-09 | — | — | CN | claimed |
| CN-111733390-A | Composite barrier material for double-reflection layer film and application thereof | 宁波瑞凌新能源科技有限公司 | 2020-10-02 | — | — | CN | claimed |
| CN-110256823-A | The economical low smell glass fibre reinforced composite material and preparation method thereof that resists cold | 江苏金发科技新材料有限公司 | 2019-09-20 | — | — | CN | claimed |
| US-7241855-B2 | Method for the manufacture of polyesters | ZIMMER AKTIENGESELLSCHAFT (DE) | 2007-07-10 | — | — | US | claimed |
| CN-111114031-B | Radiation refrigeration film, radiation refrigeration composite film and radiation refrigeration product | 宁波瑞凌新能源科技有限公司 | 2022-05-03 | — | — | CN | disclosed |
| CN-111751916-A | Barrier layer film structure and application thereof | 宁波瑞凌新能源科技有限公司 | 2020-10-09 | — | — | CN | disclosed |
| CN-111733390-A | Composite barrier material for double-reflection layer film and application thereof | 宁波瑞凌新能源科技有限公司 | 2020-10-02 | — | — | CN | disclosed |
| CN-210617539-U | Radiation cooling material and composite material thereof | 宁波瑞凌新能源科技有限公司 | 2020-05-26 | — | — | CN | disclosed |
| CN-111114031-A | Radiation refrigeration film, radiation refrigeration composite film and radiation refrigeration product | 宁波瑞凌新能源科技有限公司 | 2020-05-08 | — | — | CN | disclosed |