Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3642195 | 0.94 | POLB (0.33) | POLB | |
| SCHEMBL11635818 | 0.83 | GRIN2D (0.36) | POLB | |
| SCHEMBL14498537 | 0.83 | GRIN2D (0.36) | POLB | |
| SCHEMBL11045613 | 0.82 | — | — | |
| SCHEMBL11045595 | 0.82 | — | — | |
| SCHEMBL5257926 | 0.80 | GRIN2D (0.31) | — | |
| SCHEMBL17837228 | 0.80 | MEN1 (0.30) | POLB | |
| SCHEMBL22468833 | 0.80 | MEN1 (0.30) | POLB | |
| SCHEMBL11795172 | 0.79 | CYP2C19 (0.34) | POLB | |
| SCHEMBL4343952 | 0.77 | MEN1 (0.31) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11236063-B2 | Dibenzofuran derivatives and dibenzothiophene derivatives | MERCK PATENT GMBH (DE) | 2022-02-01 | — | — | US | disclosed |
| US-20210139451-A1 | DIBENZOFURAN DERIVATIVES AND DIBENZOTHIOPHENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2021-05-13 | — | — | US | disclosed |
| CN-110770219-A | Dibenzofurane and dibenzothiophene derivatives | 默克专利股份有限公司 | 2020-02-07 | — | — | CN | disclosed |
| JP-2007099711-A | METHOD FOR PRODUCTION OF OPTICALLY ACTIVE CYCLOPENTANONES AND PRODUCTION INTERMEDIATE THEREOF | TAKASAGO INTERNATL CORP | 2007-04-19 | — | — | JP | disclosed |
| CN-1031971-C | (Benzylidene)-azolylmethylcycloalkane and use as fungicide | RHONE POULENC AGROCHIMIE (FR) | 1996-06-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11236063-B2 | Dibenzofuran derivatives and dibenzothiophene derivatives | DDT, EDF1, DBF4 | POLB 4500/4885 |
| US-20210139451-A1 | DIBENZOFURAN DERIVATIVES AND DIBENZOTHIOPHENE DERIVATIVES | DDT, DBF4, EDF1 | POLB 4689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.