Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.80 |
| ▸ | GAA | P10253 | 11/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.80 |
| ▸ | RAB9A | P51151 | 4/20 | 0.80 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.80 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.80 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.74 |
| ▸ | HPGD | P15428 | 5/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5370506 | 0.88 | GAA (0.80) | MAPTGAAALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL2250301 | 0.87 | GAA (0.68) | MAPTGAAALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL5372147 | 0.84 | GAA (0.66) | MAPTGAAALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL5425036 | 0.83 | NR1H4 (0.62) | MAPTGAAALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL5373182 | 0.76 | NR1H4 (0.63) | MAPTGAAALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL2251270 | 0.76 | GAA (0.68) | MAPTGAAALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL2253516 | 0.76 | GAA (0.74) | MAPTGAAALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL2252724 | 0.75 | GAA (0.75) | MAPTGAAALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL31344185 | 0.74 | MAPT (0.79) | MAPTGAAALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL6285593 | 0.72 | NR1H4 (0.48) | MAPTGAAALDH1A1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007067711-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS FOR MODULATING TRPV1 | AMPHORA DISCOVERY CORPORATION (US) | 2007-06-14 | — | — | WO | disclosed |