Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 16/20 | 0.80 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5310079 | 0.89 | LTA4H (1.00) | LTA4HMEN1KMT2AHPGDMCHR2 | |
| SCHEMBL5310076 | 0.89 | LTA4H (1.00) | LTA4HMEN1KMT2AHPGDMCHR2 | |
| SCHEMBL5314309 | 0.89 | LTA4H (1.00) | LTA4HMEN1KMT2AHPGDMCHR2 | |
| SCHEMBL5310075 | 0.87 | LTA4H (1.00) | LTA4HMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL5316021 | 0.87 | LTA4H (1.00) | LTA4HMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL5310068 | 0.87 | LTA4H (1.00) | LTA4HMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL5312417 | 0.86 | LTA4H (0.87) | LTA4HMEN1KMT2AHPGDLMNA | |
| SCHEMBL5315339 | 0.84 | LTA4H (0.87) | LTA4HMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL5311002 | 0.83 | LTA4H (0.87) | LTA4HMEN1KMT2AHPGD | |
| SCHEMBL5310544 | 0.77 | LTA4H (1.00) | LTA4HMCHR2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007079003-A2 | AMIDE INHIBITORS OF LEUKOTRIENE A4 HYDROLASE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-07-12 | — | — | WO | disclosed |