SCHEMBL5375209

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Cp-778875 SCHEMBL1600965	0.91	POLB (0.58)	POLBCASP6GFERPABPC1ALDH1A1
	SCHEMBL5391181	0.90	POLB (0.54)	POLBCASP6GFERPABPC1ALDH1A1
	SCHEMBL5388054	0.89	POLB (0.56)	POLBCASP6GFERPABPC1ALDH1A1
	SCHEMBL14437715	0.89	POLB (0.56)	POLBCASP6GFERPABPC1ALDH1A1
	SCHEMBL5376629	0.89	CASP6 (0.52)	POLBCASP6GFERPABPC1ALDH1A1
	SCHEMBL5386741	0.89	POLB (0.56)	POLBCASP6GFERPABPC1ALDH1A1
	SCHEMBL5390814	0.89	POLB (0.58)	POLBCASP6GFERPABPC1ALDH1A1
	SCHEMBL5376861	0.89	POLB (0.56)	POLBCASP6GFERPABPC1ALDH1A1
	SCHEMBL5373188	0.89	POLB (0.55)	POLBCASP6GFERPABPC1ALDH1A1
	SCHEMBL5375322	0.88	POLB (0.54)	POLBCASP6GFERPABPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.