Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.61 |
| ▸ | PPARG | P37231 | 16/20 | 0.61 |
| ▸ | PPARD | Q03181 | 8/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5386189 | 0.86 | PPARA (0.81) | PPARAPPARGPPARD | |
| SCHEMBL5395118 | 0.85 | PPARG (0.62) | PPARAPPARGPPARDMAPT | |
| SCHEMBL6529018 | 0.85 | PPARG (0.62) | PPARAPPARGPPARDMAPT | |
| SCHEMBL14571181 | 0.84 | PPARG (0.64) | PPARAPPARGPPARDFFAR1 | |
| SCHEMBL27674846 | 0.83 | PPARA (0.84) | PPARAPPARGPPARD | |
| SCHEMBL5383883 | 0.83 | PPARA (0.84) | PPARAPPARGPPARD | |
| SCHEMBL5383887 | 0.83 | PPARA (0.84) | PPARAPPARGPPARD | |
| SCHEMBL5374934 | 0.80 | PPARA (0.74) | PPARAPPARGPPARD | |
| SCHEMBL14560354 | 0.79 | PPARG (0.76) | PPARAPPARGPPARDMAPT | |
| SCHEMBL5375774 | 0.79 | PPARG (0.92) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7192982-B2 | Modulators of peroxisome proliferator activated receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2007-03-20 | — | — | US | disclosed |
| US-20050020684-A1 | Modulators of peroxisome proliferator activated receptors | ELI LILLY AND COMPANY | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020684-A1 | Modulators of peroxisome proliferator activated receptors | NCOA4, PPARG, PPARA | PPARA 3/4885PPARG 2/4885PPARD 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.