Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.62 |
| ▸ | PPARA | Q07869 | 10/20 | 0.62 |
| ▸ | PPARD | Q03181 | 8/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5395118 | 1.00 | PPARG (0.62) | PPARGPPARAPPARDKMT2AMEN1 | |
| SCHEMBL5385227 | 0.91 | PPARG (0.65) | PPARGPPARAPPARDNPC1POLB | |
| SCHEMBL5374720 | 0.89 | PPARG (0.62) | PPARGPPARAPPARDKMT2AMEN1 | |
| SCHEMBL5375428 | 0.85 | PPARA (0.61) | PPARGPPARAPPARDMAPT | |
| SCHEMBL5386189 | 0.84 | PPARA (0.81) | PPARGPPARAPPARD | |
| SCHEMBL5385663 | 0.83 | PPARG (0.62) | PPARGPPARAPPARDNPC1RAB9A | |
| SCHEMBL6575710 | 0.83 | PPARG (0.62) | PPARGPPARAPPARDNPC1RAB9A | |
| SCHEMBL5395103 | 0.82 | PPARG (0.62) | PPARGPPARAPPARDKMT2AMEN1 | |
| SCHEMBL5381113 | 0.82 | PPARG (0.62) | PPARGPPARAPPARDKMT2AMEN1 | |
| SCHEMBL5383401 | 0.82 | PPARG (0.61) | PPARGPPARAPPARDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050020684-A1 | Modulators of peroxisome proliferator activated receptors | ELI LILLY AND COMPANY | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020684-A1 | Modulators of peroxisome proliferator activated receptors | NCOA4, PPARG, PPARA | PPARG 2/4885PPARA 3/4885PPARD 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.