SCHEMBL5375632

SCHEMBL5375632

CO[Si](OC)(OC)C(OCC1CO1)C(C)C

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.35
TSHR P16473 2/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4753557 0.85
SCHEMBL5379297 0.84 ALDH1A1 (0.34) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL5379300 0.82 SMN1; SMN2 (0.34) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL231370 0.81 ALDH1A1 (0.38) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL5368311 0.80 SMN1; SMN2 (0.40) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL5598583 0.78 ALDH1A1 (0.35) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL5364785 0.77 SMN1; SMN2 (0.49) ALDH1A1TSHRSMN1; SMN2TDP1
SCHEMBL5598253 0.75 ALDH1A1 (0.33) ALDH1A1TSHRMAPK1SMN1; SMN2TP53
SCHEMBL23673323 0.74 ALDH1A1 (0.37) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL28764 0.74 ALDH1A1 (0.37) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070251448-A1 Application method, applicator, optical member, and optical device SAKURADA KAZUAKI 2007-11-01 US disclosed
US-7250190-B2 Application method, applicator, optical member, and optical device SEIKO EPSON CORPORATION (JP) 2007-07-31 US disclosed
US-6773465-B1 Optical element ITOH OPTICAL INDUSTRIAL CO., LTD. (JP) 2004-08-10 US disclosed
US-20040142105-A1 Application method, applicator, optical member, and optical device SEIKO EPSON CORPORATION (JP) 2004-07-22 US disclosed