SCHEMBL5375645

SCHEMBL5375645

CC(Oc1ccccc1)(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 7/20 0.55
ESR2 Q92731 7/20 0.55
CYP3A4 P08684 3/20 0.55
ALDH1A1 P00352 3/20 0.55
LTA4H P09960 1/20 0.48
NR1H2 P55055 1/20 0.48
BAX Q07812 1/20 0.48
LMNA P02545 2/20 0.46
SLC6A2 P23975 2/20 0.46
SLC6A3 Q01959 2/20 0.46
TYR P14679 1/20 0.46
AR P10275 1/20 0.46
HPGD P15428 1/20 0.46
TSHR P16473 1/20 0.46
SLC6A4 P31645 1/20 0.46
HTR6 P50406 1/20 0.46
ESRRG P62508 1/20 0.46
HSD17B10 Q99714 1/20 0.46
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6566057 0.85 MAPK1 (0.48) ESR1ESR2CYP3A4ALDH1A1LTA4H
SCHEMBL21191327 0.84 ESR1 (0.55) ESR1ESR2CYP3A4ALDH1A1LTA4H
SCHEMBL20763441 0.82 ESR1 (0.53) ESR1ESR2CYP3A4ALDH1A1LTA4H
SCHEMBL27936073 0.78 ESR1 (0.52) ESR1ESR2CYP3A4ALDH1A1LTA4H
Phenol SCHEMBL28126814 0.77 CA4 (0.50) ESR1ESR2CYP3A4ALDH1A1LTA4H
SCHEMBL27210407 0.76 ESR1 (0.55) ESR1ESR2CYP3A4ALDH1A1LTA4H
Phenol SCHEMBL28085355 0.76 ALDH1A1 (0.52) ESR1ESR2CYP3A4ALDH1A1LTA4H
Bisphenol A SCHEMBL2463040 0.76 ESR1 (0.73) ESR1ESR2CYP3A4ALDH1A1LTA4H
SCHEMBL1835505 0.76 ESR1 (0.52) ESR1ESR2CYP3A4ALDH1A1LTA4H
SCHEMBL27936140 0.76 ESR1 (0.47) ESR1ESR2CYP3A4ALDH1A1LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2007262415-A TETRAPHENOL AND THEIR USE AS POLYCARBONATE BRANCHING AGENTS GENERAL ELECTRIC CO <GE> 2007-10-11 JP disclosed
EP-0819718-B1 Tetraphenol polycarbonate branching agents GEN ELECTRIC (US) 2003-05-14 EP disclosed
EP-0819469-B1 Quaternary bisphenolates as phase transfer catalysts GEN ELECTRIC (US) 2001-11-21 EP disclosed
US-5969086-A CONTACTING ALKALI METAL SALT OF DIHYDROXYAROMATIC COMPOUND WITH HALO- OR NITRO-SUBSTITUTED AROMATIC COMPOUND IN PRESENCE OF CATALYTIC AMOUNT OF ALKALINE HYDROLYSIS PRODUCT OF QUATERNARY SALT OF DIHYDROXYAROMATIC COMPOUND GENERAL ELECTRIC COMPANY (US) 1999-10-19 US disclosed
US-5863992-A BISPHENOL A FOR POLYCARBONATES GENERAL ELECTRIC COMPANY (US) 1999-01-26 US disclosed
US-5756843-A REACTING DIHYDROXYAROMATIC COMPOUND, ALKALI METAL HYDROXIDE AND QUATERNARY SALT GENERAL ELECTRIC COMPANY (US) 1998-05-26 US disclosed
CN-1172822-A Tetraphenols and their use as polycarbonate branching agents GEN ELECTRIC (US) 1998-02-11 CN disclosed
EP-0819718-A1 Tetraphenol polycarbonate branching agents GENERAL ELECTRIC COMPANY (US) 1998-01-21 EP disclosed
EP-0819718-A1 Tetraphenol polycarbonate branching agents GENERAL ELECTRIC COMPANY (US) 1998-01-21 EP disclosed
EP-0819469-A2 Quaternary bisphenolates as phase transfer catalysts GENERAL ELECTRIC COMPANY (US) 1998-01-21 EP disclosed