Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | ALPI | P09923 | 1/20 | 0.58 |
| ▸ | XIAP | P98170 | 1/20 | 0.58 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.54 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.54 |
| ▸ | TPH1 | P17752 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL588601 | 1.00 | SLC7A5 (0.58) | SLC7A5PTGS1PKMALPIXIAP | |
| SCHEMBL537570 | 1.00 | SLC7A5 (0.58) | SLC7A5PTGS1PKMALPIXIAP | |
| SCHEMBL10927828 | 0.85 | ALOX5 (0.50) | SLC7A5PTGS1PKMALPIXIAP | |
| SCHEMBL7608944 | 0.82 | SLC7A5 (0.56) | SLC7A5PTGS1PKMALPIXIAP | |
| SCHEMBL7608948 | 0.82 | SLC7A5 (0.56) | SLC7A5PTGS1PKMALPIXIAP | |
| SCHEMBL6779373 | 0.78 | SLC1A3 (0.44) | SLC7A5PTGS1PKMALPIXIAP | |
| SCHEMBL2310526 | 0.78 | SLC7A5 (0.83) | SLC7A5PTGS1PKMALPIXIAP | |
| SCHEMBL2671472 | 0.76 | CYP1A2 (0.46) | PTGS1SLC1A3SLC1A2SLC1A1ALOX5 | |
| SCHEMBL9812650 | 0.76 | — | — | |
| SCHEMBL23159186 | 0.74 | SLC7A5 (1.00) | SLC7A5PTGS1PKMALPIXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9434764-B2 | Skin care compositions and methods comprising selective agonists of melanocortin 1 receptor | UNIVERSITY OF CINCINNATI (US) | 2016-09-06 | — | — | US | claimed |
| US-20150299251-A1 | Skin Care Compositions and Methods Comprising Selective Agonists of Melanocortin 1 Receptor | UNIVERSITY OF CINCINNATI (US) | 2015-10-22 | — | — | US | claimed |
| US-20150297667-A1 | PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC METHODS OF USE COMPRISING SELECTIVE AGONISTS OF MELANOCORTIN 1 RECEPTOR | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-10-22 | — | — | US | claimed |
| EP-2925340-A2 | PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC METHODS OF USE COMPRISING SELECTIVE AGONISTS OF MELANOCORTIN 1 RECEPTOR | University Of Cincinnati (US) | 2015-10-07 | — | — | EP | claimed |
| EP-2922565-A2 | SKIN CARE COMPOSITIONS AND METHODS COMPRISING SELECTIVE AGONISTS OF MELANOCORTIN 1 RECEPTOR | University Of Cincinnati (US) | 2015-09-30 | — | — | EP | claimed |
| WO-2014081846-A2 | PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC METHODS OF USE COMPRISING SELECTIVE AGONISTS OF MELANOCORTIN 1 RECEPTOR | UNIVERSITY OF CINCINNATI (US) | 2014-05-30 | — | — | WO | claimed |
| WO-2014081845-A2 | SKIN CARE COMPOSITIONS AND METHODS COMPRISING SELECTIVE AGONISTS OF MELANOCORTIN 1 RECEPTOR | UNIVERSITY OF CINCINNATI (US) | 2014-05-30 | — | — | WO | claimed |
| EP-1297826-A1 | Nasal pharmaceutical compositions containing a NK-2 antagonist | Menarini Ricerche S.p.A. (IT) | 2003-04-02 | — | — | EP | claimed |
| EP-0815126-B1 | BICYCLIC TACHYKININS ANTAGONISTS, PREPARATION THEREOF AND THEIR USE IN PHARMACEUTICAL COMPOSITION | MENARINI FARMA IND (IT) | 2001-01-03 | — | — | EP | claimed |
| US-6150325-A | FOR TREATMENT OF ARTHRITIS, ASTHMA, INFLAMMATIONS, TUMORAL GROWTH, GASTROINTESTINAL HYPERMOTILITY, HUNTINGTON'S DISEASE, NEURITIS, NEURALGIA, HEMICRANIA, HYPERTENSION, URINARY INCONTINENCE, URTICARIA | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 2000-11-21 | — | — | US | claimed |
| WO-1996028467-A1 | BICYCLIC TACHYKININS ANTAGONISTS, PREPARATION THEREOF AND THEIR USE IN PHARMACEUTICAL COMPOSITION | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1996-09-19 | — | — | WO | claimed |
| EP-0636146-A1 | TACHYKININ ANTAGONIST TRICYCLIC COMPOUNDS, PREPARATION OF SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS. | MENARINI FARMA IND (IT) | 1995-02-01 | — | — | EP | claimed |
| EP-0276014-B1 | Anticoagulant peptides | MERRELL DOW PHARMA (US) | 1994-08-31 | — | — | EP | claimed |
| EP-0255082-B1 | Renin-inhibiting di- and tripeptides, methods for their production, drugs containing them, and their use | HOECHST AG (DE) | 1993-12-01 | — | — | EP | claimed |
| WO-1993021227-A1 | TACHYKININ ANTAGONIST TRICYCLIC COMPOUNDS, PREPARATION OF SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1993-10-28 | — | — | WO | claimed |
| EP-0373549-B1 | AMINO ACID DERIVATIVES WITH ENZYME-INHIBITING PROPERTIES, PROCESS TO SYNTHETISE THEM, COMPOSITION CONTAINING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-01 | — | — | EP | claimed |
| US-5204357-A | RENIN-INHIBITING AMINO ACID DERIVATIVES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-04-20 | — | — | US | claimed |
| EP-0394853-A1 | Dipeptide-derivatives with enzym-inhibiting activity | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-31 | — | — | EP | claimed |
| EP-0394829-A1 | Renin-inhibiting dipeptides, process to synthetize them, compositions containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-31 | — | — | EP | claimed |
| US-4855286-A | HYPOTENSIVE AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-08 | — | — | US | claimed |