Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 5/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.48 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.48 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.48 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.48 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.48 |
| ▸ | HTR3B | O95264 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602318 | 0.75 | CHRM3 (0.58) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL2360214 | 0.72 | CHRM3 (0.61) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL21095684 | 0.72 | CHRM3 (0.61) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL2360215 | 0.72 | CHRM3 (0.61) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL30934916 | 0.70 | KDM4E (0.54) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL9601555 | 0.68 | CHRM3 (0.55) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL21095667 | 0.68 | CHRM3 (0.82) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL21095668 | 0.68 | CHRM3 (0.82) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL6052211 | 0.68 | CHRM3 (0.82) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL7209230 | 0.67 | CHRM3 (0.80) | CHRM3CHRM2CHRM1CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828179-A2 | NICOTINIC ALPHA-7 RECEPTOR LIGANDS AND PREPARATION AND USES THEREOF | Memory Pharmaceutical Corporation (US) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006069097-A2 | NICOTINIC ALPHA-7 RECEPTOR LIGANDS AND PREPARATION AND USES THEREOF | MEMORY PHARMACEUTICALS CORPORATION (US) | 2006-06-29 | — | — | WO | disclosed |