⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL82647 | 0.97 | — | — | |
| SCHEMBL27622656 | 0.95 | — | — | |
| SCHEMBL8992680 | 0.95 | — | — | |
| SCHEMBL29470047 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL29850352 | 0.95 | — | — | |
| SCHEMBL27491306 | 0.95 | — | — | |
| Benzene SCHEMBL28198430 | 0.91 | MGAM (0.48) | — | |
| SCHEMBL31568721 | 0.89 | GAA (0.52) | — | |
| Ethyl Acetate SCHEMBL11626551 | 0.83 | ALDH1A1 (0.54) | — | |
| Naphthalene SCHEMBL28174978 | 0.83 | GAA (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114369033-B | Green preparation method of N, N-dimethylamino ethyl acrylate | 江苏飞宇医药科技股份有限公司 | 2023-01-31 | — | — | CN | claimed |
| CN-114369033-A | Green preparation method of N, N-dimethylamino ethyl acrylate | 江苏飞宇医药科技股份有限公司 | 2022-04-19 | — | — | CN | claimed |
| CN-111039870-B | Preparation method of polyhalogenated methyl pyrazole formate | 浙江本立科技股份有限公司 | 2022-03-22 | — | — | CN | claimed |
| CN-111039870-A | Preparation method of polyhalogenated methyl pyrazole formate | 浙江本立科技股份有限公司 | 2020-04-21 | — | — | CN | claimed |
| CN-110003119-A | A kind of preparation method of 5- methyl -5- phenyl barbiturates | 山东新华制药股份有限公司 | 2019-07-12 | — | — | CN | claimed |
| US-20190009255-A1 | CORE-SHELL STRUCTURE SUPPORTED TUNGSTEN COMPOSITE CATALYST AND PREPARATION METHOD AND USE THEREOF | ZHEJIANG BENLI TECHNOLOGY CO., LTD. (CN) | 2019-01-10 | — | — | US | claimed |
| CN-108440562-A | A kind of synthetic method of Levofloxacin pharmaceutical intermediate | 邳州易萨新型材料有限公司 | 2018-08-24 | — | — | CN | claimed |
| CN-108404990-A | A kind of catalyst and its application for synthesizing Levofloxacin pharmaceutical intermediate | 邳州易萨新型材料有限公司 | 2018-08-17 | — | — | CN | claimed |
| CN-105367431-B | 3 N of one kind, the preparation method of N dimethylamino ethyl acrylates | 吉林普瑞特生物科技有限公司 | 2017-07-14 | — | — | CN | claimed |
| CN-103896856-A | Multi-substituted monocyclopyrimidine JNK (Jun N Terminal) kinase inhibitor as well as preparation method and use thereof | YE LONG | 2014-07-02 | — | — | CN | claimed |
| CN-102675217-A | Preparation method of 5-bromine-2-methyl-4(1H)-pyrimidone | CGENE TECH SUZHOU CHINA CO LTD | 2012-09-19 | — | — | CN | claimed |
| EP-0132851-B1 | 5-SUBSTITUTED(1,2,4)TRIAZOLO(1,5-C)PYRIMIDIN-2-AMINES | AMERICAN CYANAMID COMPANY (US) | 1989-10-04 | — | — | EP | claimed |
| CN-112979560-B | Method for preparing uracil | 爱斯特（成都）生物制药股份有限公司 | 2023-03-24 | — | — | CN | disclosed |
| CN-114369033-B | Green preparation method of N, N-dimethylamino ethyl acrylate | 江苏飞宇医药科技股份有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-114369033-B | Green preparation method of N, N-dimethylamino ethyl acrylate | 江苏飞宇医药科技股份有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-112300018-B | Preparation method of N, N-dimethylamino ethyl acrylate | 宿迁市科莱博生物化学有限公司 | 2022-12-13 | — | — | CN | disclosed |
| US-4558126-A | Method of preparing uracil | DYNAMIT NOBEL AG (DE) | 1985-12-10 | — | — | US | disclosed |
| US-4515984-A | Process for the preparation of alkali-metal formyl acid esters | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) | 1985-05-07 | — | — | US | disclosed |
| EP-0132851-A1 | 5-Substituted(1,2,4)triazolo(1,5-c)pyrimidin-2-amines | AMERICAN CYANAMID COMPANY (US) | 1985-02-13 | — | — | EP | disclosed |
| US-4476306-A | Method of preparing 2,4-dihydroxypyrimidine | DYNAMIT NOBEL AG (DE) | 1984-10-09 | — | — | US | disclosed |