Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 11/20 | 0.35 |
| ▸ | PPARA | Q07869 | 8/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | TACR2 | P21452 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5376297 | 1.00 | ENPP2 (0.36) | ENPP2PPARGPPARACYP2C9KCNH2 | |
| SCHEMBL5342918 | 0.95 | ENPP2 (0.37) | ENPP2PPARGPPARACYP2C9KCNH2 | |
| SCHEMBL5342922 | 0.95 | ENPP2 (0.37) | ENPP2PPARGPPARACYP2C9KCNH2 | |
| SCHEMBL5359999 | 0.91 | NPSR1 (0.38) | ENPP2PPARGCYP2C9F2RL3CYP1A2 | |
| SCHEMBL5359991 | 0.91 | NPSR1 (0.38) | ENPP2PPARGCYP2C9F2RL3CYP1A2 | |
| SCHEMBL5317489 | 0.91 | ENPP2 (0.38) | ENPP2PPARGPPARACYP2C9KCNH2 | |
| SCHEMBL5317486 | 0.91 | ENPP2 (0.38) | ENPP2PPARGPPARACYP2C9KCNH2 | |
| SCHEMBL5337864 | 0.90 | ENPP2 (0.38) | ENPP2PPARGPPARACYP2C9KCNH2 | |
| SCHEMBL5337868 | 0.90 | ENPP2 (0.38) | ENPP2PPARGPPARACYP2C9KCNH2 | |
| SCHEMBL5318741 | 0.86 | ENPP2 (0.39) | ENPP2PPARGCYP2C9PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786424-A2 | LONIDAMINE ANALOGUES AND THEIR USE IN MALE CONTRACEPTION AND CANCER TREATMENT | The University of Kansas (US) | 2007-05-23 | — | — | EP | claimed |
| WO-2006023704-A2 | LONIDAMINE ANALOGUES AND THEIR USE IN MALE CONTRACEPTION AND CANCER TREATMENT | UNIVERSITY OF KANSAS (US) | 2006-03-02 | — | — | WO | claimed |