Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 19/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5343741 | 0.90 | PTH1R (0.80) | PTH1R | |
| SCHEMBL5324368 | 0.88 | PTH1R (0.67) | PTH1R | |
| SCHEMBL5362367 | 0.86 | PTH1R (0.84) | PTH1R | |
| SCHEMBL14386442 | 0.85 | PTH1R (0.83) | PTH1R | |
| SCHEMBL5328196 | 0.85 | PTH1R (0.52) | PTH1R | |
| SCHEMBL5363635 | 0.85 | PTH1R (0.82) | PTH1R | |
| SCHEMBL5355799 | 0.84 | PTH1R (0.98) | PTH1R | |
| SCHEMBL5369142 | 0.83 | PTH1R (0.79) | PTH1R | |
| SCHEMBL5367699 | 0.83 | PTH1R (0.76) | PTH1R | |
| SCHEMBL5368169 | 0.82 | PTH1R (0.69) | PTH1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135417-A1 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-11-29 | — | — | WO | disclosed |