Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10389241 | 0.97 | MAPK1 (0.41) | MAPK1KMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL29352953 | 0.97 | MAPK1 (0.41) | MAPK1KMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL10389212 | 0.97 | MAPK1 (0.41) | MAPK1KMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL28715240 | 0.97 | MAPK1 (0.41) | MAPK1KMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL1598214 | 0.85 | KMT2A (0.49) | MAPK1KMT2AMEN1GAATHRB | |
| SCHEMBL3110403 | 0.84 | KMT2A (0.51) | MAPK1KMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL30591631 | 0.84 | HSP90AB1 (0.39) | MAPK1KMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL163966 | 0.84 | HSP90AB1 (0.39) | MAPK1KMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL8182271 | 0.80 | KMT2A (0.45) | KMT2AMEN1GAATHRBKDM4E | |
| SCHEMBL5749312 | 0.80 | NOS3 (0.34) | MAPK1KMT2AMEN1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 573 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114933568-B | Preparation method of 4, 6-dimethyl-2-methylsulfonyl pyrimidine | 抚州润泰药业有限公司 | 2024-11-26 | — | — | CN | claimed |
| CN-118307483-A | Preparation method of 2-methylsulfonyl-4, 6-dimethoxy pyrimidine | 新沂大江化工有限公司 | 2024-07-09 | — | — | CN | claimed |
| US-20240154124-A1 | NEGATIVE ELECTRODE PLATE AND LITHIUM-ION BATTERY COMPRISING SAME | ZHUHAI COSMX BATTERY CO., LTD. (CN) | 2024-05-09 | — | — | US | claimed |
| CN-220257206-U | 4-6-dihydroxy-2-methylthiopyrimidine hydrothermal recrystallization kettle | 江苏鸣翔化工有限公司 | 2023-12-29 | — | — | CN | claimed |
| CN-114933568-A | Preparation method of 4, 6-dimethyl-2-methylsulfonyl pyrimidine | 抚州润泰药业有限公司 | 2022-08-23 | — | — | CN | claimed |
| CN-110372605-B | Synthesis method of 2-methylthio-4, 6-dichloro-5-nitropyrimidine | 南京普锐达医药科技有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-112552244-A | Production process of 4, 6-dimethoxy-2-methylsulfonyl pyrimidine | 内蒙古科硕新材料科技有限公司 | 2021-03-26 | — | — | CN | claimed |
| CN-110372605-A | Synthesis method of 2-methylthio-4, 6-dichloro-5-nitropyrimidine | 南京普锐达医药科技有限公司 | 2019-10-25 | — | — | CN | claimed |
| CN-109851565-A | A kind of preparation method of the chloro- 2- methylthiopyrimidine of 4,6- bis- | 苏州华诺医药有限公司 | 2019-06-07 | — | — | CN | claimed |
| CN-105026376-B | Process for the preparation of bispyribac-sodium and intermediates thereof | 加尔达化学有限公司 | 2018-05-11 | — | — | CN | claimed |
| WO-2014128719-A2 | PROCESSES FOR THE PREPARATION OF BISPYRIBAC SODIUM AND INTERMEDIATES THEREOF | GHARDA CHEMICALS LTD (IN) | 2014-08-28 | — | — | WO | claimed |
| US-7384533-B2 | Electrolytic processes with reduced cell voltage and gas formation | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-06-10 | — | — | US | claimed |
| CN-1396158-A | Process for synthesizing 4,6-dimethoxy-2-methiopyrimidine | UNIV ZHEJIANG POLYTECHNIC (CN) | 2003-02-12 | — | — | CN | claimed |
| CN-1343665-A | Process for preparing 4,6-dichloro-2-methiopyrimidine | SHAXING CHEMICAL CO LTD TAIZHO (CN) | 2002-04-10 | — | — | CN | claimed |
| US-20250313554-A1 | PTPN2 INHIBITORS | MONDEGO BIO, LDA. (PT) | 2025-10-09 | — | — | US | disclosed |
| EP-4522594-A1 | PTPN2 INHIBITORS | Ness Therapeutics, Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| CN-114933568-B | Preparation method of 4, 6-dimethyl-2-methylsulfonyl pyrimidine | 抚州润泰药业有限公司 | 2024-11-26 | — | — | CN | disclosed |
| US-4059696-A | INSECTICIDE, MITICIDE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-22 | — | — | US | disclosed |
| US-4045561-A | Pesticidal pyrimidinyl phosphorus esters | SANDOZ LTD. (CH) | 1977-08-30 | — | — | US | disclosed |
| US-3931180-A | Substituted 6-hydroxy pyrimidines | SANDOZ LTD., (SANDOZ AG) (CH) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250313554-A1 | PTPN2 INHIBITORS | PTPN2, PTPN1, PTPRJ | MAPK1 190/4885KMT2A 1912/4885MEN1 3303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.