SCHEMBL5377451

SCHEMBL5377451

C=C(C)C(=O)OCCCCOCCCCOCCCCOCCCCOCCCCOCCCCOCCCCOCCCCOCCCCOC(=O)C(=C)C

nearest known ligand 0.70

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.70
THRB P10828 1/20 0.61
POLB P06746 1/20 0.51
APEX1 P27695 1/20 0.51
HTT P42858 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
ALDH1A1 P00352 6/20 0.42
CES2 O00748 1/20 0.38
CYP3A4 P08684 1/20 0.37
NAAA Q02083 1/20 0.34
HPGD P15428 1/20 0.33
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
RAD52 P43351 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
EPHX1 P07099 1/20 0.32
TP53 P04637 1/20 0.32
HIF1A Q16665 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9066617 1.00 TSHR (0.70) TSHRTHRBPOLBAPEX1HTT
SCHEMBL9066855 1.00 TSHR (0.70) TSHRTHRBPOLBAPEX1HTT
SCHEMBL5909705 1.00 TSHR (0.70) TSHRTHRBPOLBAPEX1HTT
SCHEMBL11039180 1.00 TSHR (0.70) TSHRTHRBPOLBAPEX1HTT
SCHEMBL9067681 1.00 TSHR (0.70) TSHRTHRBPOLBAPEX1HTT
SCHEMBL17830155 1.00 TSHR (0.70) TSHRTHRBPOLBAPEX1HTT
SCHEMBL9066211 1.00 TSHR (0.70) TSHRTHRBPOLBAPEX1HTT
SCHEMBL9066861 1.00 TSHR (0.70) TSHRTHRBPOLBAPEX1HTT
SCHEMBL9066134 1.00 TSHR (0.70) TSHRTHRBPOLBAPEX1HTT
SCHEMBL8850814 1.00 TSHR (0.70) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0430209-A2 Resin composition for cast polymerization MITSUBISHI RAYON CO., LTD. (JP) 1991-06-05 EP claimed
JP-3218335-A None JP disclosed
CN-100534749-C Device for manufacturing plastic lens SEIKO EPSON CORP (JP) 2009-09-02 CN disclosed
US-7249941-B2 Device for manufacturing plastic lens SEIKO EPSON CORPORATION (JP) 2007-07-31 US disclosed
CN-1852801-A Apparatus for manufacturing plastic lens SEIKO EPSON CORP (JP) 2006-10-25 CN disclosed
US-20060012889-A1 Resin composition for hybrid lens, method for producing hybrid lens, hybrid lens and lens system SEIKO ESPON CORPORATION (JP) 2006-01-19 US disclosed
EP-1617240-A1 RESIN COMPOSITION FOR HYBRID LENS, METHOD FOR PRODUCING HYBRID LENS, HYBRID LENS AND LENS SYSTEM SEIKO EPSON CORPORATION (JP) 2006-01-18 EP disclosed
US-20050112225-A1 Device for manufacturing plastic lens SEIKO EPSON CORPORATION 2005-05-26 US disclosed
EP-0661307-B1 Transparent resin and plastic lens HITACHI CHEMICAL CO LTD (JP) 1997-10-15 EP disclosed
US-5663264-A OF A COPOLYMER CONTAINING AN ALKYLENE OXIDE MONOMER, A POLYFUNCTIONAL (METH)ACRYLATE MONOMER AND A VINYL MONOMER HITACHI CHEMICAL COMPANY, LTD. (JP) 1997-09-02 US disclosed
US-5583191-A FORMED OF TRANSPARENT RESIN OBTAINED BY POLYMERIZING MONOMER HAVING ALKYLENE OXIDE GROUP, POLYFUNCTIONAL (METH)ACRYLATE HAVING DIVALENT BRANCED HYDROCARBON GROUP, OPTIONAL ADDITIONAL VINYL MONOMER; HEAT RESISTANCE HITACHI CHEMICAL COMPANY, LTD. (JP) 1996-12-10 US disclosed
EP-0441383-B1 Use of a copolymer for the making of contact lenses MITSUBISHI RAYON CO (JP) 1996-05-08 EP disclosed
EP-0430209-B1 Resin composition for cast polymerization MITSUBISHI RAYON CO (JP) 1996-02-28 EP disclosed
EP-0661307-A2 Transparent resin and plastic lens HITACHI CHEMICAL CO., LTD. (JP) 1995-07-05 EP disclosed
US-5247038-A Optical materials MITSUBISHI RAYON CO., LTD. (JP) 1993-09-21 US disclosed
US-5183870-A A curable polybutylene glycol di(meth)acrylate, a urethane or epoxy (meth)acrylate and a (meth)acrylate; heat and water resistance; impact strength; dyeability; workability MITSUBISHI RAYON CO., LTD (JP) 1993-02-02 US disclosed
JP-H03218335-A POLYBUTYLENEGLYCOL DIMETHACRYLATE AND FLEXIBLE AND LOW WATER-ABSORPTIVE COMPOSITION CONTAINING THE SAME COMPOUND MITSUBISHI RAYON CO LTD 1991-09-25 JP disclosed
EP-0441383-A2 Use of a copolymer for the making of contact lenses MITSUBISHI RAYON CO., LTD. (JP) 1991-08-14 EP disclosed
EP-0430209-A2 Resin composition for cast polymerization MITSUBISHI RAYON CO., LTD. (JP) 1991-06-05 EP disclosed