Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.70 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9066617 | 1.00 | TSHR (0.70) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5909705 | 1.00 | TSHR (0.70) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11039180 | 1.00 | TSHR (0.70) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9067681 | 1.00 | TSHR (0.70) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL17830155 | 1.00 | TSHR (0.70) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9066211 | 1.00 | TSHR (0.70) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9066861 | 1.00 | TSHR (0.70) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9066134 | 1.00 | TSHR (0.70) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8850814 | 1.00 | TSHR (0.70) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5377451 | 1.00 | TSHR (0.70) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430209-B1 | Resin composition for cast polymerization | MITSUBISHI RAYON CO (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5247038-A | Optical materials | MITSUBISHI RAYON CO., LTD. (JP) | 1993-09-21 | — | — | US | disclosed |
| EP-0430209-A2 | Resin composition for cast polymerization | MITSUBISHI RAYON CO., LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |