⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003119 | 0.86 | SHBG (0.44) | — | |
| Methyl Alcohol SCHEMBL8209878 | 0.82 | SHBG (0.41) | — | |
| SCHEMBL12180366 | 0.82 | — | — | |
| SCHEMBL23178116 | 0.80 | — | — | |
| SCHEMBL140295 | 0.75 | — | — | |
| SCHEMBL14962377 | 0.75 | — | — | |
| SCHEMBL1193150 | 0.71 | — | — | |
| SCHEMBL8675545 | 0.71 | SHBG (0.42) | — | |
| SCHEMBL14384218 | 0.69 | — | — | |
| SCHEMBL4654274 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3002283-B1 | THIAZOLE DERIVATIVES | KYOWA HAKKO KIRIN CO LTD (JP) | 2017-06-14 | — | — | EP | disclosed |
| CN-102659683-B | Process for production of 5-alkoxy-4-hydroxymethylpyrazole compound | IHARA CHEMICAL IND CO | 2014-11-12 | — | — | CN | disclosed |
| CN-102659683-A | Process for production of 5-alkoxy-4-hydroxymethylpyrazole compound | IHARA CHEMICAL IND CO | 2012-09-12 | — | — | CN | disclosed |
| CN-101384556-B | Process for producing 5-alkoxy-4-hydroxymethylpyrazole compound | IHARA CHEMICAL IND CO | 2012-06-20 | — | — | CN | disclosed |
| EP-2277873-B1 | Intermediate compound for the preparation of halichondrin analogs | EISAI R&D MAN CO LTD (JP) | 2012-05-30 | — | — | EP | disclosed |
| EP-1990336-B1 | PROCESS FOR PRODUCTION OF 5-ALKOXY-4-HYDROXYMETHYLPYRAZOLE COMPOUND | IHARA CHEMICAL IND CO (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-7812175-B2 | Process for production of 5-alkoxy-4-hydroxymethylpyrazole compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-10-12 | — | — | US | disclosed |
| US-7529504-B2 | Organic photoconductor, process cartridge and image forming apparatus both employing the same | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2009-05-05 | — | — | US | disclosed |
| CN-101384556-A | Process for producing 5-alkoxy-4-hydroxymethylpyrazole compound | IHARA CHEMICAL IND CO (JP) | 2009-03-11 | — | — | CN | disclosed |
| US-20090036688-A1 | Process for Production of 5-Alkoxy-4-Hydroxymethylpyrazole Compound | IHARA CHEMICAL INDUSTRY CO., LTD (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1990336-A1 | PROCESS FOR PRODUCTION OF 5-ALKOXY-4-HYDROXYMETHYLPYRAZOLE COMPOUND | Ihara Chemical Industry Co., Ltd. (JP) | 2008-11-12 | — | — | EP | disclosed |