⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1995961 | 1.00 | — | — | |
| SCHEMBL7626529 | 1.00 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL8625739 | 0.74 | — | — | |
| SCHEMBL8625997 | 0.74 | — | — | |
| SCHEMBL114258 | 0.71 | TSHR (0.35) | — | |
| SCHEMBL15786373 | 0.71 | TSHR (0.35) | — | |
| SCHEMBL15780501 | 0.71 | TSHR (0.35) | — | |
| SCHEMBL6519713 | 0.71 | — | — | |
| SCHEMBL18807102 | 0.71 | TSHR (0.35) | — | |
| SCHEMBL10778141 | 0.71 | TSHR (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187805-B1 | PROCESS FOR PREPARING R-(-)-CARNITINE FROM S-(-)-CHLOROSUCCINIC ACID OR FROM A DERIVATIVE THEREOF | SIGMA TAU IND FARMACEUTI (IT) | 2006-11-29 | — | — | EP | claimed |
| US-6984739-B2 | Process for preparing R-(−)-carnitin from S-(−)-chlorosuccinic acid or from a derivative thereof | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2006-01-10 | — | — | US | claimed |
| EP-1468979-A1 | Process for preparing S-(-)-chlorosuccinic acid | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 2004-10-20 | — | — | EP | claimed |
| US-20040102645-A1 | Process for preparing R-(-)-carnitin from S-(-)-chlorosuccinic acid or from a derivative thereof | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2004-05-27 | — | — | US | claimed |
| US-6677476-B1 | REDUCING HALO- OR SULFONYLOXY-SUCCINIC ACID OR DERIVATIVE WITH SUITABLE REDUCING AGENT, TREATING WITH BASE AND THEN WITH TRIMETHYLAMINE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2004-01-13 | — | — | US | claimed |
| EP-1187805-A1 | PROCESS FOR PREPARING R-(-)-CARNITINE FROM S-(-)-CHLOROSUCCINIC ACID OR FROM A DERIVATIVE THEREOF | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 2002-03-20 | — | — | EP | claimed |
| WO-2000069808-A1 | PROCESS FOR PREPARING R-(-)-CARNITINE FROM S-(-)-CHLOROSUCCINIC ACID OR FROM A DERIVATIVE THEREOF | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2000-11-23 | — | — | WO | claimed |
| US-7247747-B2 | Process for preparing R-(-)carnitine from S-(-)-chlorosuccinic acid or from a derivative thereof | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2007-07-24 | — | — | US | disclosed |
| US-7247747-B2 | Process for preparing R-(-)carnitine from S-(-)-chlorosuccinic acid or from a derivative thereof | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2007-07-24 | — | — | US | disclosed |
| US-7247747-B2 | Process for preparing R-(-)carnitine from S-(-)-chlorosuccinic acid or from a derivative thereof | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2007-07-24 | — | — | US | disclosed |
| EP-1187805-B1 | PROCESS FOR PREPARING R-(-)-CARNITINE FROM S-(-)-CHLOROSUCCINIC ACID OR FROM A DERIVATIVE THEREOF | SIGMA TAU IND FARMACEUTI (IT) | 2006-11-29 | — | — | EP | disclosed |
| US-6984739-B2 | Process for preparing R-(−)-carnitin from S-(−)-chlorosuccinic acid or from a derivative thereof | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2006-01-10 | — | — | US | disclosed |
| US-20050245762-A1 | Process for preparing R-(-)carnitine from S-(-)-chlorosuccinic acid or from a derivative thereof | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2005-11-03 | — | — | US | disclosed |
| EP-1468979-A1 | Process for preparing S-(-)-chlorosuccinic acid | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 2004-10-20 | — | — | EP | disclosed |
| US-20040102645-A1 | Process for preparing R-(-)-carnitin from S-(-)-chlorosuccinic acid or from a derivative thereof | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2004-05-27 | — | — | US | disclosed |
| US-6677476-B1 | REDUCING HALO- OR SULFONYLOXY-SUCCINIC ACID OR DERIVATIVE WITH SUITABLE REDUCING AGENT, TREATING WITH BASE AND THEN WITH TRIMETHYLAMINE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2004-01-13 | — | — | US | disclosed |
| EP-1187805-A1 | PROCESS FOR PREPARING R-(-)-CARNITINE FROM S-(-)-CHLOROSUCCINIC ACID OR FROM A DERIVATIVE THEREOF | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 2002-03-20 | — | — | EP | disclosed |
| WO-2000069808-A1 | PROCESS FOR PREPARING R-(-)-CARNITINE FROM S-(-)-CHLOROSUCCINIC ACID OR FROM A DERIVATIVE THEREOF | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2000-11-23 | — | — | WO | disclosed |