Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5374681 | 0.85 | PDE2A (0.33) | PDE2A | |
| SCHEMBL5388686 | 0.82 | CYP1A2 (0.32) | — | |
| Bromide SCHEMBL5373790 | 0.76 | IDO1 (0.33) | — | |
| SCHEMBL5376510 | 0.71 | — | — | |
| SCHEMBL5378880 | 0.68 | ALOX5AP (0.39) | — | |
| SCHEMBL537622 | 0.67 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL5378099 | 0.67 | MEN1 (0.32) | — | |
| SCHEMBL34467245 | 0.67 | CYP1A2 (0.34) | — | |
| SCHEMBL1028460 | 0.67 | ALOX5AP (0.32) | — | |
| SCHEMBL26103877 | 0.66 | MEN1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1541561-B1 | PYRAZOLE DERIVATIVES AND PROCESS FOR THE PRODUCTION THEREOF | IHARA CHEMICAL IND CO (JP) | 2014-07-23 | — | — | EP | disclosed |
| US-20070249844-A1 | Pyrazole derivatives and process for the production thereof | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-10-25 | — | — | US | disclosed |
| US-7256298-B2 | Pyrazole derivatives and process for the production thereof | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-08-14 | — | — | US | disclosed |
| US-20050215797-A1 | Pyrazole derivatives and process for the production thereof | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-09-29 | — | — | US | disclosed |
| EP-1541561-A1 | PYRAZOLE DERIVATIVES AND PROCESS FOR THE PRODUCTION THEREOF | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2005-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249844-A1 | Pyrazole derivatives and process for the production thereof | CBR3, CYP4Z1, CYP4F3 | PDE2A 2659/4885MAP3K12 2634/4885 |
| US-20050215797-A1 | Pyrazole derivatives and process for the production thereof | CBR3, CYP4Z1, CYP4F3 | PDE2A 2659/4885MAP3K12 2634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.