Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALML3 | P27482 | 6/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14370650 | 1.00 | CALML3 (0.46) | CALML3SIGMAR1GRM2MAOAMAOB | |
| SCHEMBL5374997 | 0.86 | F10 (0.44) | CALML3GRM2MAOAMAOB | |
| SCHEMBL14370645 | 0.86 | F10 (0.44) | CALML3GRM2MAOAMAOB | |
| SCHEMBL14370651 | 0.86 | GRM2 (0.41) | SIGMAR1GRM2 | |
| SCHEMBL14370644 | 0.84 | F10 (0.45) | CALML3SIGMAR1MAOAMAOB | |
| SCHEMBL5375233 | 0.83 | MAOA (0.53) | MAOAMAOB | |
| SCHEMBL14370652 | 0.83 | MAOA (0.53) | MAOAMAOB | |
| SCHEMBL14224728 | 0.78 | MAOA (0.54) | CALML3MAOAMAOB | |
| SCHEMBL4881816 | 0.78 | MAOA (0.54) | CALML3MAOAMAOB | |
| SCHEMBL5383280 | 0.77 | MAOA (0.51) | CALML3SIGMAR1GRM2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279494-B2 | Antimicrobial [3.1.0] bicyclohexylphenyl-oxazolidinone derivatives and analogues | PFIZER INC. (US) | 2007-10-09 | — | — | US | disclosed |
| US-20050192325-A1 | Antimicrobial [3.1.0] bicyclohexylphenyl-oxazolidinone derivatives and analogues | RENSLO ADAM (US) | 2005-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050192325-A1 | Antimicrobial [3.1.0] bicyclohexylphenyl-oxazolidinone derivatives and analogues | OXA1L, CYP51A1, CYP2C19 | CALML3 3870/4885SIGMAR1 450/4885GRM2 3931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.