Methylene Chloride

Methylene Chloride

SCHEMBL5378948

ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.NCCCN

nearest known ligand 0.55

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 1/20 0.55
DNM1 Q05193 4/20 0.50
CA12 O43570 3/20 0.50
CA2 P00918 3/20 0.50
CA4 P22748 3/20 0.50
CA6 P23280 3/20 0.50
CA5A P35218 3/20 0.50
CA7 P43166 3/20 0.50
CA9 Q16790 3/20 0.50
CA14 Q9ULX7 3/20 0.50
CA5B Q9Y2D0 3/20 0.50
CA1 P00915 2/20 0.50
CA3 P07451 2/20 0.50
TSHR P16473 2/20 0.50
LMNA P02545 1/20 0.50
BLM P54132 1/20 0.50
ALDH1A1 P00352 2/20 0.40
CASP2 P42575 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8182 0.84
SCHEMBL16345592 0.84 NFKB1 (0.75) NFKB1DNM1CA12CA2CA4
SCHEMBL7267804 0.84 NFKB1 (0.75) NFKB1DNM1CA12CA2CA4
Chloromethane SCHEMBL9186830 0.80 NFKB1 (0.55) NFKB1DNM1CA12CA2CA4
SCHEMBL25350595 0.78
Iodide SCHEMBL19180051 0.78
Hydrochloric Acid SCHEMBL158471 0.78
Hydrochloric Acid SCHEMBL423991 0.78
Fluoride SCHEMBL21296519 0.78
Water SCHEMBL11771535 0.78 NFKB1 (0.67) NFKB1DNM1CA12CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7204927-B2 Settling aids for solids in hydrocarbons GE BETZ, INC. (US) 2007-04-17 US claimed
WO-2004043889-A1 SETTLING AIDS FOR SOLIDS IN HYDROCARBONS GE BETZ, INC. (US) 2004-05-27 WO claimed
US-20040089590-A1 Settling aids for solids in hydrocarbons GE BETZ, INC. 2004-05-13 US claimed
US-5476988-A Adding quaternary fatty ammonium compound to fluid catalytic cracking slurry to coagulate catalyst fines BETZ LABORATORIES, INC. (US) 1995-12-19 US claimed
US-5476988-A Adding quaternary fatty ammonium compound to fluid catalytic cracking slurry to coagulate catalyst fines BETZ LABORATORIES, INC. (US) 1995-12-19 US disclosed