SCHEMBL537918

SCHEMBL537918

CCC(C)OC1(CC)OC(=O)CC(=O)O1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9052163 0.79 PTGS1 (0.31)
SCHEMBL9752077 0.73 SMN1; SMN2 (0.30)
SCHEMBL8115152 0.71 SORT1 (0.31)
SCHEMBL28375809 0.68 POLB (0.31)
SCHEMBL32679710 0.66 KDM4E (0.30)
SCHEMBL2710911 0.65 PTPN1 (0.40)
SCHEMBL8124758 0.65 SORT1 (0.35)
SCHEMBL8053864 0.63 PTPN1 (0.42)
SCHEMBL4783712 0.63
SCHEMBL14021455 0.63 PIK3CD (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1171097-A1 A PHARMACEUTICAL FORMULATION COMPRISING AN BISPHOSPHONATE AND AN ADDITIVE AGENT PROVIDING AN ENHANCED ABSORPTION OF THE BISPHOSPHONATE AstraZeneca AB (SE) 2002-01-16 EP claimed
EP-0816353-B1 New coumarin derivatives, processes for the preparation thereof and their use PLIVA PHARM & CHEM WORKS (HR) 2001-12-19 EP claimed
EP-0799052-B1 NEW ANTITHROMBOTIC FORMULATION, PROCESS FOR ITS MANUFACTURING, AND USE THEREOF ASTRAZENECA AB (SE) 2001-11-14 EP claimed
WO-2000061111-A1 A PHARMACEUTICAL FORMULATION COMPRISING AN BISPHOSPHONATE AND AN ADDITIVE AGENT PROVIDING AN ENHANCED ABSORPTION OF THE BISPHOSPHONATE ASTRAZENECA AB (SE) 2000-10-19 WO claimed
WO-1999006401-A1 2-ARYL-2,5-DIHYDRO-PYRAZOLO[4,3-c]QUINOLIN-3-ONES AS GABA ALPHA 5 RECEPTOR INVERSE AGONISTS MERCK SHARP & DOHME LIMITED (GB) 1999-02-11 WO claimed
US-5840922-A Coumarin derivatives, and processes for their preparation PLIVA, FARMACEUTSKA, KEMIJSKA, PREHRAMBENA I KOZMETICKA INDUSTRIJA, DIONICKO DRUSTVO (HR) 1998-11-24 US claimed
US-5795896-A Antithrombotic formulation, process for its manufacturing, and use thereof ASTRA AKTIEBOLAG (SE) 1998-08-18 US claimed
EP-0816353-A2 New coumarin derivatives, processes for the preparation thereof and their use PLIVA farmaceutska, kemijska, prehrambena i kozmeticka industrija, dionicko drustvo (HR) 1998-01-07 EP claimed
EP-0799052-A1 NEW ANTITHROMBOTIC FORMULATION, PROCESS FOR ITS MANUFACTURING, AND USE THEREOF Astra Aktiebolag (SE) 1997-10-08 EP claimed
WO-1996016671-A1 NEW ANTITHROMBOTIC FORMULATION, PROCESS FOR ITS MANUFACTURING, AND USE THEREOF ASTRA AKTIEBOLAG (SE) 1996-06-06 WO claimed
CN-119504571-A Right-embedded alcohol or fenchyl alcohol ester derivatives of 2-hydroxy nicotinic acid and pharmaceutical application thereof 苏州缘聚医药科技有限公司 2025-02-25 CN disclosed
EP-3694516-B1 BIODEGRADABLE QUINOLONE ANTIBIOTICS LEUPHANA UNIV LUENEBURG STIFTUNG OEFFENTLICHEN RECHTS (DE) 2023-12-13 EP disclosed
CN-113950473-A Next generation modulators of interferon gene Stimulators (STING) 雷沃医疗有限公司 2022-01-18 CN disclosed
CN-105694749-B Pressure-sensitive adhesive sheet for use in semiconductor production 日东电工株式会社 2020-07-24 CN disclosed
CN-110869363-A 5-membered and bicyclic heterocyclic amides as ROCK inhibitors 百时美施贵宝公司 2020-03-06 CN disclosed
EP-0055068-A1 Quinolone derivatives and their use as pharmaceuticals Lilly Industries Limited (GB) 1982-06-30 EP disclosed
US-4211562-A Photographic compositions with silver halide solvents containing thioether groups POLAROID CORPORATION (US) 1980-07-08 US disclosed
US-4211559-A Photographic processes and compositions employing thioether containing silver halide solvents TEXAS INSTRUMENTS INCORPORATED (US) 1980-07-08 US disclosed
US-4150228-A PHOTOGRAPHIC COMPLEXING AGENTS POLAROID CORPORATION (US) 1979-04-17 US disclosed
US-4126459-A COMPLEXING AGENT FOR USE IN PHOTOGRAPHY POLAROID CORPORATION (US) 1978-11-21 US disclosed