SCHEMBL537954

SCHEMBL537954

C=C[SiH](OCCCCC)OCCCCC

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.37
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.34
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA9 Q16790 2/20 0.32
THRB P10828 2/20 0.32
MEN1 O00255 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
CA12 O43570 1/20 0.32
MAPT P10636 1/20 0.32
HCAR2 Q8TDS4 1/20 0.31
CES1 P23141 1/20 0.31
LPAR1 Q92633 2/20 0.31
LPAR3 Q9UBY5 2/20 0.31
LPAR2 Q9HBW0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28753814 0.98 TSHR (0.41) TSHRCA1CA2CA9THRB
SCHEMBL1260599 0.93 TSHR (0.40) TSHRALDH1A1HPGDCA1CA2
SCHEMBL81525 0.82 TSHR (0.30) TSHR
SCHEMBL15302119 0.81 TSHR (0.37) TSHRALDH1A1HPGDCA1CA2
SCHEMBL10488778 0.80 LPAR2 (0.42) TSHRLPAR1LPAR3LPAR2
SCHEMBL16548062 0.77 TSHR (0.39) TSHRCA1CA2CA9THRB
SCHEMBL29179308 0.76 TSHR (0.38) TSHRCA1CA2CA9THRB
SCHEMBL15302339 0.73 TSHR (0.40) TSHRALDH1A1HPGDCA1CA2
SCHEMBL7937314 0.73 TSHR (0.39) TSHRALDH1A1HPGDCA1CA2
SCHEMBL15090851 0.73 TSHR (0.39) TSHRALDH1A1HPGDCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9074032-B2 Membranes based on polyvinyl alcohol WACKER CHEMIE AG (DE) 2015-07-07 US claimed
EP-2414411-B1 MEMBRANES BASED ON POLYVINYL ALCOHOL WACKER CHEMIE AG (DE) 2013-02-20 EP claimed
US-20120031843-A1 Membranes based on polyvinyl alcohol WACKER CHEMIE AG (DE) 2012-02-09 US claimed
EP-2414411-A2 MEMBRANES BASED ON POLYVINYL ALCOHOL Wacker Chemie AG (DE) 2012-02-08 EP claimed
WO-2010112372-A2 MEMBRANES BASED ON POLYVINYL ALCOHOL WACKER CHEMIE AG (DE) 2010-10-07 WO claimed
US-20160046827-A1 FILM COMPRISING COPOLYMER OR COMPOSITION MITSUI CHEMICALS, INC. (JP) 2016-02-18 US disclosed
EP-2985301-A1 COPOLYMER AND HYDROPHILIC MATERIAL COMPRISING SAME Mitsui Chemicals, Inc. (JP) 2016-02-17 EP disclosed
EP-2985324-A1 FILM COMPRISING COPOLYMER OR COMPOSITION Mitsui Chemicals, Inc. (JP) 2016-02-17 EP disclosed
US-20160032036-A1 COPOLYMER AND HYDROPHILIC MATERIAL COMPOSED OF THE SAME MITSUI CHEMICALS, INC. (JP) 2016-02-04 US disclosed
US-9074032-B2 Membranes based on polyvinyl alcohol WACKER CHEMIE AG (DE) 2015-07-07 US disclosed
EP-2414411-B1 MEMBRANES BASED ON POLYVINYL ALCOHOL WACKER CHEMIE AG (DE) 2013-02-20 EP disclosed
US-20120031843-A1 Membranes based on polyvinyl alcohol WACKER CHEMIE AG (DE) 2012-02-09 US disclosed
EP-2414411-A2 MEMBRANES BASED ON POLYVINYL ALCOHOL Wacker Chemie AG (DE) 2012-02-08 EP disclosed
WO-2010112372-A2 MEMBRANES BASED ON POLYVINYL ALCOHOL WACKER CHEMIE AG (DE) 2010-10-07 WO disclosed
US-6051665-A A FLUOROPOLYMER IS OBTAINED FROM THE MONOMER SELECTED FROM THE GROUP CONTAINING A FLUORO-OLEFIN, A FLUORO VINYL ETHER, A FLUORO (METH) ACRYLATE AND MIXTURE, ALSO CONTAIN HYDROLYZABLE SILYL GROUP, A SILOXY COMPOUND AND A CHELATE COMPLEX JSR CORPORATION (JP) 2000-04-18 US disclosed
US-5332779-A Polymerizable silica sol, adamantane derivative for use in the sol and cured resin prepared using the same KAWASAKI STEEL CORPORATION (JP) 1994-07-26 US disclosed
EP-0460560-A2 Polymerizable silica sol, adamantane derivative for use in the sol and cured resin prepared using the same KAWASAKI STEEL CORPORATION (JP) 1991-12-11 EP disclosed