Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5371113 | 1.00 | F10 (0.47) | F10 | |
| SCHEMBL5380049 | 0.90 | F10 (0.39) | F10 | |
| SCHEMBL5386312 | 0.90 | F10 (0.39) | F10 | |
| SCHEMBL5380531 | 0.89 | F10 (0.38) | F10 | |
| SCHEMBL5379823 | 0.89 | F10 (0.38) | F10 | |
| SCHEMBL5386580 | 0.87 | F10 (0.38) | F10 | |
| SCHEMBL5380643 | 0.87 | F10 (0.34) | F10 | |
| SCHEMBL5371161 | 0.87 | F10 (0.34) | F10 | |
| SCHEMBL5383367 | 0.85 | F10 (0.36) | F10 | |
| SCHEMBL5377448 | 0.83 | HDAC8 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7235544-B2 | for use in conjunction with thrombolytic agents, thus permitting the use of a lower dose of thrombolytic agent; treatment of acute vascular diseases; may have potential in neurogenerative diseases such as Parkinson's and Alzheimer's disease | GLAXO GROUP LIMITED (GB) | 2007-06-26 | — | — | US | disclosed |