Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.69 |
| ▸ | CDC14B | O60729 | 1/20 | 0.51 |
| ▸ | CDC14A | Q9UNH5 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12037130 | 0.91 | ALOX5 (0.59) | ALOX5CDC14BCDC14ASMN1; SMN2ALDH1A1 | |
| SCHEMBL16582801 | 0.91 | ALOX5 (0.70) | ALOX5CDC14BCDC14ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12037217 | 0.90 | ALOX5 (0.58) | ALOX5CDC14BCDC14ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3865828 | 0.89 | ALOX5 (0.69) | ALOX5CDC14BCDC14ASMN1; SMN2ALDH1A1 | |
| SCHEMBL24171048 | 0.89 | ALOX5 (0.68) | ALOX5CDC14BCDC14ASMN1; SMN2ALDH1A1 | |
| SCHEMBL431876 | 0.87 | ALOX5 (0.66) | ALOX5CDC14BCDC14ASMN1; SMN2ALDH1A1 | |
| SCHEMBL18698053 | 0.86 | ALOX5 (0.64) | ALOX5CDC14BCDC14ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12324537 | 0.86 | ALOX5 (0.64) | ALOX5CDC14BCDC14ASMN1; SMN2ALDH1A1 | |
| SCHEMBL30257190 | 0.86 | ALOX5 (0.64) | ALOX5CDC14BCDC14ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11712766 | 0.85 | ALOX5 (0.63) | ALOX5CDC14BCDC14ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170298077-A1 | HETEROCYCLIC COMPOUNDS WITH BENZO(C)COUMARIN-STRUCTURES | MERCK PATENT GMBH (DE) | 2017-10-19 | — | — | US | disclosed |
| US-9735373-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2017-08-15 | — | — | US | disclosed |
| US-9735373-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2017-08-15 | — | — | US | disclosed |
| US-9735373-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2017-08-15 | — | — | US | disclosed |
| US-20140361252-A1 | ALUMINUM CHELATES AS MATERIALS FOR OLEDS | UNIVERSAL DISPLAY CORPORATION (US) | 2014-12-11 | — | — | US | disclosed |
| US-20140361252-A1 | ALUMINUM CHELATES AS MATERIALS FOR OLEDS | UNIVERSAL DISPLAY CORPORATION (US) | 2014-12-11 | — | — | US | disclosed |
| US-20140361252-A1 | ALUMINUM CHELATES AS MATERIALS FOR OLEDS | UNIVERSAL DISPLAY CORPORATION (US) | 2014-12-11 | — | — | US | disclosed |
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | BROOKS DAWN A | 2007-11-29 | — | — | US | disclosed |
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | BROOKS DAWN A | 2007-11-29 | — | — | US | disclosed |
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | BROOKS DAWN A | 2007-11-29 | — | — | US | disclosed |
| US-7192982-B2 | Modulators of peroxisome proliferator activated receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2007-03-20 | — | — | US | disclosed |
| US-7192982-B2 | Modulators of peroxisome proliferator activated receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2007-03-20 | — | — | US | disclosed |
| US-7192982-B2 | Modulators of peroxisome proliferator activated receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2007-03-20 | — | — | US | disclosed |
| US-20050020684-A1 | Modulators of peroxisome proliferator activated receptors | ELI LILLY AND COMPANY | 2005-01-27 | — | — | US | disclosed |
| EP-1392637-A2 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | ELI LILLY AND COMPANY (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002100813-A2 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | ELI LILLY AND COMPANY (US) | 2002-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170298077-A1 | HETEROCYCLIC COMPOUNDS WITH BENZO(C)COUMARIN-STRUCTURES | NISCH, SIRT3, NQO1 | ALOX5 2630/4885CDC14B 3740/4885CDC14A 3399/4885 |
| US-20050020684-A1 | Modulators of peroxisome proliferator activated receptors | NCOA4, PPARG, PPARA | ALOX5 1617/4885CDC14B 4356/4885CDC14A 4336/4885 |
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | PPARG, NCOA4, PPARA | ALOX5 1600/4885CDC14B 4451/4885CDC14A 4441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.