⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4477365 | 0.93 | RAF1 (0.30) | — | |
| SCHEMBL4466426 | 0.91 | RAF1 (0.31) | — | |
| SCHEMBL4478888 | 0.85 | — | — | |
| SCHEMBL4489060 | 0.84 | — | — | |
| SCHEMBL4473261 | 0.80 | MOGAT2 (0.31) | — | |
| SCHEMBL4465580 | 0.79 | — | — | |
| SCHEMBL4466276 | 0.76 | SHMT2 (0.33) | — | |
| SCHEMBL4487441 | 0.75 | — | — | |
| SCHEMBL4477929 | 0.75 | STING1 (0.31) | — | |
| SCHEMBL4470788 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781662-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | Pfizer, Inc. (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006018725-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2006-02-23 | — | — | WO | disclosed |