Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | BUB1 | O43683 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.38 |
| ▸ | ITK | Q08881 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3825068 | 0.87 | PIK3C3 (0.44) | CDC7NPC1PIK3C3 | |
| SCHEMBL3827756 | 0.83 | PIK3C3 (0.53) | BUB1KMT2AMEN1SMN1; SMN2CDC7 | |
| SCHEMBL5380286 | 0.80 | GSK3B (0.54) | BUB1MAPTHTTSMN1; SMN2TP53 | |
| SCHEMBL3832211 | 0.79 | CA1 (0.54) | BUB1KMT2AMEN1NPC1 | |
| SCHEMBL5632811 | 0.76 | SMN1; SMN2 (0.53) | GCGRMAPK14KMT2AMEN1RAB9A | |
| SCHEMBL5400013 | 0.75 | NCOA1 (0.53) | GCGRMAPK14BUB1KMT2AMEN1 | |
| SCHEMBL3830998 | 0.75 | MEN1 (0.54) | GCGRMAPK14BUB1KMT2AMEN1 | |
| SCHEMBL3847348 | 0.75 | BUB1 (0.49) | BUB1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL5632242 | 0.74 | BUB1 (0.49) | BUB1KMT2AMEN1MAPTHTT | |
| SCHEMBL5399975 | 0.74 | CDC7 (0.48) | GCGRMAPK14SMN1; SMN2HPGDCDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7256199-B1 | Pyrimidone derivatives | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-08-14 | — | — | US | claimed |
| US-7256199-B1 | Pyrimidone derivatives | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-08-14 | — | — | US | disclosed |