Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5385849 | 0.79 | HDAC4 (0.37) | HDAC4HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL10634051 | 0.78 | CRHBP (0.38) | HDAC4SLC6A2SLC6A4SLC6A3SSTR4 | |
| SCHEMBL5398627 | 0.75 | BAZ2B (0.33) | SLC6A2 | |
| SCHEMBL28767790 | 0.74 | HTR2A (0.40) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3115682 | 0.66 | HDAC4 (0.42) | HDAC4CES2BCHECES1HDAC3 | |
| SCHEMBL29240149 | 0.66 | HTR2A (0.41) | SLC6A2SLC6A4SLC6A3 | |
| Pirepemat SCHEMBL28355846 | 0.66 | HDAC4 (0.40) | HDAC4CES2BCHECES1HDAC3 | |
| SCHEMBL1329573 | 0.65 | HDAC4 (0.42) | HDAC4CES2BCHECES1HDAC3 | |
| SCHEMBL30824567 | 0.65 | HDAC4 (0.42) | HDAC4CES2BCHECES1HDAC3 | |
| SCHEMBL5101790 | 0.65 | HDAC4 (0.39) | HDAC4CES2BCHECES1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238691-B2 | Piperidine derivatives and their use as modulators of chemokine (especially CCR3) activity | ASTRAZENECA AB (SE) | 2007-07-03 | — | — | US | disclosed |