SCHEMBL5380464

SCHEMBL5380464

Oc1ccc(-c2cccc3c2sc2ccccc23)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.69
PARP14 Q460N5 1/20 0.52
HSP90AA1 P07900 2/20 0.47
APP P05067 2/20 0.45
PTPN1 P18031 3/20 0.44
GPR3 P46089 1/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
ABL1 P00519 1/20 0.43
ABCB1 P08183 1/20 0.43
BCR P11274 1/20 0.43
PRKDC P78527 1/20 0.41
LMNA P02545 3/20 0.40
MAPT P10636 3/20 0.40
KDM4E B2RXH2 2/20 0.40
NPC1 O15118 2/20 0.40
ALDH1A1 P00352 2/20 0.40
RAB9A P51151 2/20 0.40
GLA P06280 1/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21152361 0.91 ALOX5 (0.70) ALOX5PARP14GPR3MEN1KMT2A
SCHEMBL17167407 0.89 ALOX5 (0.68) ALOX5PARP14GPR3MEN1KMT2A
SCHEMBL15893248 0.89 ALOX5 (0.68) ALOX5PARP14GPR3MEN1KMT2A
SCHEMBL429297 0.87 ALOX5 (0.66) ALOX5PARP14GPR3MEN1KMT2A
SCHEMBL30150735 0.86 ALOX5 (0.64) ALOX5PARP14GPR3MEN1KMT2A
SCHEMBL17117671 0.86 ALOX5 (0.64) ALOX5PARP14GPR3MEN1KMT2A
SCHEMBL18435735 0.86 ALOX5 (0.64) ALOX5PARP14GPR3MEN1KMT2A
SCHEMBL29362337 0.85 ALOX5 (0.63) ALOX5PARP14GPR3MEN1KMT2A
SCHEMBL2810404 0.85 ALOX5 (0.63) ALOX5PARP14GPR3MEN1KMT2A
SCHEMBL16534775 0.85 ALOX5 (0.68) ALOX5PARP14HSP90AA1APPPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12041847-B2 Compound for organic electric element, organic electric element using the same, and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2024-07-16 US disclosed
EP-2910553-A1 Organic electroluminescent materials and devices Universal Display Corporation (US) 2015-08-26 EP disclosed
US-20070276138-A1 Modulators of peroxisome proliferator activated receptors BROOKS DAWN A 2007-11-29 US disclosed
CN-101061111-A DNA-PK inhibitors KUDOS PHARM LTD (GB) 2007-10-24 CN disclosed
US-7192982-B2 Modulators of peroxisome proliferator activated receptors LIGAND PHARMACEUTICALS, INC. (US) 2007-03-20 US disclosed
US-20050020684-A1 Modulators of peroxisome proliferator activated receptors ELI LILLY AND COMPANY 2005-01-27 US disclosed
EP-1392637-A2 MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS ELI LILLY AND COMPANY (US) 2004-03-03 EP disclosed
WO-2002100813-A2 MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS ELI LILLY AND COMPANY (US) 2002-12-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12041847-B2 Compound for organic electric element, organic electric element using the same, and electronic device thereof ORAI2, OR51E2, OR10J3 ALOX5 820/4885PARP14 2611/4885HSP90AA1 4745/4885
US-20050020684-A1 Modulators of peroxisome proliferator activated receptors NCOA4, PPARG, PPARA ALOX5 1617/4885PARP14 1558/4885HSP90AA1 2432/4885
US-20070276138-A1 Modulators of peroxisome proliferator activated receptors PPARG, NCOA4, PPARA ALOX5 1600/4885PARP14 1800/4885HSP90AA1 2277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.