Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | IDH2 | P48735 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5382823 | 0.91 | BACE1 (0.36) | GAATSHRSMN1; SMN2BACE1KMT2A | |
| SCHEMBL5382840 | 0.91 | BACE1 (0.36) | GAATSHRSMN1; SMN2BACE1KMT2A | |
| SCHEMBL5400967 | 0.90 | MEN1 (0.39) | TSHRSMN1; SMN2BACE1KMT2AMEN1 | |
| SCHEMBL5450599 | 0.89 | IKBKB (0.37) | SMN1; SMN2BACE1IDH2NPSR1PTGS2 | |
| SCHEMBL5387743 | 0.89 | SLC2A1 (0.44) | GAABACE1KMT2AMEN1POLB | |
| SCHEMBL5383855 | 0.88 | ALDH1A1 (0.39) | GAASMN1; SMN2BACE1IDH2NPSR1 | |
| SCHEMBL5432333 | 0.87 | IKBKB (0.37) | GAASMN1; SMN2BACE1PTGS2RAD52 | |
| SCHEMBL5396035 | 0.87 | RAD52 (0.43) | TSHRSMN1; SMN2KMT2AMEN1IDH2 | |
| SCHEMBL5387709 | 0.86 | EP300 (0.41) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5392542 | 0.85 | KMT2A (0.42) | GAABACE1KMT2AMEN1IDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |