⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24445152 | 0.80 | HTR2A (0.35) | — | |
| SCHEMBL25628707 | 0.65 | — | — | |
| SCHEMBL18945785 | 0.64 | — | — | |
| SCHEMBL23129542 | 0.64 | — | — | |
| SCHEMBL14143250 | 0.63 | CHRNB2 (0.31) | — | |
| SCHEMBL13859912 | 0.63 | CHRNB2 (0.31) | — | |
| SCHEMBL19513021 | 0.63 | — | — | |
| SCHEMBL18617949 | 0.62 | — | — | |
| SCHEMBL14015905 | 0.62 | — | — | |
| SCHEMBL18513512 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460797-A2 | Process for preparation of ivabradine hydrochloride | Cadila Healthcare Limited (IN) | 2012-06-06 | — | — | EP | disclosed |
| EP-2097383-B1 | Process for preparation of ivabradine hydrochloride | CADILA HEALTHCARE LTD (IN) | 2012-02-08 | — | — | EP | disclosed |
| EP-2097383-A2 | PROCESS FOR PREPARATION OF IVABRADINE HYDROCHLORIDE | Cadila Healthcare Limited (IN) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008065681-A2 | PROCESS FOR PREPARATION OF IVABRADINE HYDROCHLORIDE | CADILA HEALTHCARE LIMITED (IN) | 2008-06-05 | — | — | WO | disclosed |