Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.55 |
| ▸ | CTSV | O60911 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5400093 | 1.00 | GSK3B (0.56) | GSK3BGPR84CTSVCTSLCDC7 | |
| SCHEMBL5376002 | 1.00 | GSK3B (0.56) | GSK3BGPR84CTSVCTSLCDC7 | |
| SCHEMBL5381257 | 0.99 | GSK3B (0.58) | GSK3BGPR84CTSVCTSLCDC7 | |
| SCHEMBL5386248 | 0.94 | GSK3B (0.63) | GSK3BGPR84CTSVCTSLCDC7 | |
| SCHEMBL5380512 | 0.89 | GSK3B (0.51) | GSK3BGPR84CDC7 | |
| SCHEMBL5399975 | 0.83 | CDC7 (0.48) | GSK3BCDC7 | |
| SCHEMBL5382469 | 0.82 | GSK3B (0.49) | GSK3BGPR84CTSVCTSLCDC7 | |
| SCHEMBL5387928 | 0.80 | GSK3B (0.65) | GSK3BCDC7 | |
| SCHEMBL5390451 | 0.79 | GSK3B (0.45) | GSK3BGPR84CTSVCTSLCDC7 | |
| SCHEMBL5376006 | 0.78 | GSK3B (0.90) | GSK3BGPR84CDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7256199-B1 | Pyrimidone derivatives | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-08-14 | — | — | US | disclosed |
| EP-1115721-B1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEM CORP (JP) | 2003-12-10 | — | — | EP | disclosed |
| EP-1115721-A1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000018758-A1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-04-06 | — | — | WO | disclosed |