Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | AGER | Q15109 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL538638 | 0.87 | KMT2A (0.48) | KMT2AMEN1HPGDHSD17B10HTT | |
| SCHEMBL3867305 | 0.76 | HPGD (0.60) | KMT2AMEN1HPGDHSD17B10HTT | |
| SCHEMBL7855409 | 0.74 | MEN1 (0.54) | KMT2AMEN1HPGDHSD17B10HTT | |
| SCHEMBL8871621 | 0.74 | MEN1 (0.54) | KMT2AMEN1HPGDHSD17B10HTT | |
| SCHEMBL5089332 | 0.74 | MEN1 (0.54) | KMT2AMEN1HPGDHSD17B10HTT | |
| SCHEMBL14740086 | 0.74 | HSD17B10 (0.54) | KMT2AMEN1HPGDHSD17B10HTT | |
| SCHEMBL16761843 | 0.74 | KMT2A (0.57) | KMT2AMEN1HPGDHSD17B10HTT | |
| SCHEMBL9696724 | 0.73 | MEN1 (0.53) | KMT2AMEN1HPGDHSD17B10HTT | |
| SCHEMBL9674221 | 0.72 | KMT2A (0.60) | KMT2AMEN1HPGDHSD17B10HTT | |
| SCHEMBL11414055 | 0.72 | MEN1 (0.51) | KMT2AMEN1HPGDHSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9074032-B2 | Membranes based on polyvinyl alcohol | WACKER CHEMIE AG (DE) | 2015-07-07 | — | — | US | disclosed |
| EP-2414411-B1 | MEMBRANES BASED ON POLYVINYL ALCOHOL | WACKER CHEMIE AG (DE) | 2013-02-20 | — | — | EP | disclosed |
| US-8137590-B2 | Particles comprising zwitterionic structural elements | WACKER CHEMIE AG (DE) | 2012-03-20 | — | — | US | disclosed |
| US-20120031843-A1 | Membranes based on polyvinyl alcohol | WACKER CHEMIE AG (DE) | 2012-02-09 | — | — | US | disclosed |
| EP-2414411-A2 | MEMBRANES BASED ON POLYVINYL ALCOHOL | Wacker Chemie AG (DE) | 2012-02-08 | — | — | EP | disclosed |
| EP-1940940-B1 | PARTICLES COMPRISING ZWITTERIONIC STRUCTURAL ELEMENTS | CONSORTIUM ELEKTROCHEM IND (DE) | 2011-04-20 | — | — | EP | disclosed |
| WO-2010112372-A2 | MEMBRANES BASED ON POLYVINYL ALCOHOL | WACKER CHEMIE AG (DE) | 2010-10-07 | — | — | WO | disclosed |
| US-20080286628-A1 | Particles Comprising Zwitterionic Structural Elements | WACKER CHEMIE AG (DE) | 2008-11-20 | — | — | US | disclosed |