⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL2064861 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL538160 | 0.95 | — | — | |
| SCHEMBL10716303 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL6508564 | 0.79 | — | — | |
| SCHEMBL8901756 | 0.76 | — | — | |
| SCHEMBL2556849 | 0.71 | — | — | |
| SCHEMBL7725 | 0.71 | — | — | |
| SCHEMBL2378433 | 0.70 | — | — | |
| Dimethylamine SCHEMBL9854037 | 0.67 | ALDH1A1 (0.56) | — | |
| Dimethylamine SCHEMBL7893155 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100284905-A1 | Methods and Agents for Inhibiting Tumor Growth by Targeting the SSDNA Replication Intermediate of Tumor Stem Cells | Massachusetts Institute of Tehnology | 2010-11-11 | — | — | US | claimed |
| EP-2171448-A2 | METHODS AND AGENTS FOR INHIBITING TUMOR GROWTH BY TARGETING THE SSDNA REPLICATION INTERMEDIATE OF TUMOR STEM CELLS | Massachusetts Institute of Technology (US) | 2010-04-07 | — | — | EP | claimed |
| WO-2008156629-A2 | METHODS AND AGENTS FOR INHIBITING TUMOR GROWTH BY TARGETING THE SSDNA REPLICATION INTERMEDIATE OF TUMOR STEM CELLS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-12-24 | — | — | WO | claimed |
| EP-0354093-B1 | Piperazine derivatives and process for their preparation | SYNTHELABO (FR) | 1993-12-22 | — | — | EP | claimed |
| EP-0354093-A1 | Piperazine derivatives and process for their preparation | SYNTHELABO (FR) | 1990-02-07 | — | — | EP | claimed |
| US-20240390331-A1 | ORAL BENDAMUSTINE FORMULATIONS | TUBE PHARMACEUTICALS GMBH (AT) | 2024-11-28 | — | — | US | disclosed |
| EP-3691637-A1 | ORAL BENDAMUSTINE FORMULATIONS | TUBE Pharmaceuticals GmbH (AT) | 2020-08-12 | — | — | EP | disclosed |
| US-20200246312-A1 | ORAL BENDAMUSTINE FORMULATIONS | TUBE PHARMACEUTICALS GMBH (AT) | 2020-08-06 | — | — | US | disclosed |
| CN-111201019-A | Oral bendamustine formulations | 图贝药物有限公司 | 2020-05-26 | — | — | CN | disclosed |
| WO-2019068904-A1 | ORAL BENDAMUSTINE FORMULATIONS | TUBE PHARMACEUTICALS GMBH (AT) | 2019-04-11 | — | — | WO | disclosed |
| CN-108290910-A | N, N-bis (2-dialkylphosphinoethyl) amine-borane complex, process for producing the same, and process for producing ruthenium complex using the amine as ligand | 高砂香料工业株式会社 | 2018-07-17 | — | — | CN | disclosed |
| US-9987211-B2 | Sunless tanning compounds and compositions | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2018-06-05 | — | — | US | disclosed |
| US-4734225-A | ANTITUMOR AGENTS | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 1988-03-29 | — | — | US | disclosed |
| EP-0256936-A1 | 4-Benzyl piperazine derivatives, their preparation and pharmaceutical compositions containing them | RHONE-POULENC SANTE (FR) | 1988-02-24 | — | — | EP | disclosed |
| EP-0225608-A2 | Medicine | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 1987-06-16 | — | — | EP | disclosed |
| EP-0083442-B1 | PROCESS FOR THE PRODUCTION OF 2,4,6-TRICHLOROANILINE | BAYER AG (DE) | 1986-08-20 | — | — | EP | disclosed |
| EP-0110795-B1 | PYRROLIDINE DERIVATIVES, THEIR PREPARATION AND MEDICINES CONTAINING THEM | RHONE-POULENC SANTE (FR) | 1986-03-12 | — | — | EP | disclosed |
| EP-0110795-A1 | Pyrrolidine derivatives, their preparation and medicines containing them | RHONE-POULENC SANTE (FR) | 1984-06-13 | — | — | EP | disclosed |
| EP-0083442-A2 | Process for the production of 2,4,6-trichloroaniline | BAYER AG (DE) | 1983-07-13 | — | — | EP | disclosed |
| US-4007180-A | POLYESTERS | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-02-08 | — | — | US | disclosed |