SCHEMBL5382

SCHEMBL5382

C[CH]c1cc[nH]n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28081467 0.80
SCHEMBL10149533 0.80
SCHEMBL20535558 0.78
SCHEMBL5713386 0.78 LMNA (0.33)
SCHEMBL294900 0.75
SCHEMBL28188612 0.75
SCHEMBL12268290 0.75
SCHEMBL3294360 0.74
SCHEMBL29709049 0.74
SCHEMBL29709064 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024022481-A1 PHENYL-SUBSTITUTED DIHYDRONAPHTHYRIDINE COMPOUNDS, AND PREPARATION AND USE THEREOF 苏中药业集团股份有限公司 2024-02-01 WO claimed
EP-4217358-A1 INDAZOLES AS HEMATOPOIETIC PROGENITOR KINASE 1 (HPK1) INHIBITORS AND METHODS OF USING SAME 1st Biotherapeutics, Inc. (KR) 2023-08-02 EP claimed
CN-111212831-B Fluorine-containing ether compound, lubricant for magnetic recording medium, and magnetic recording medium 株式会社力森诺科 2023-06-16 CN claimed
US-11649255-B2 Indazoles as hematopoietic progenitor kinase 1 (HPK1) inhibitors and methods using same 1ST Biotherapeutics, Inc. (KR) 2023-05-16 US claimed
CN-110997625-B Fluorinated ether compound, lubricant for magnetic recording medium, and magnetic recording medium 昭和电工株式会社 2023-03-31 CN claimed
CN-111032625-B Fluorinated ether compound, lubricant for magnetic recording medium, and magnetic recording medium 昭和电工株式会社 2022-12-09 CN claimed
CN-108690016-B Pyrazolopyridines and uses thereof 广东东阳光药业有限公司 2022-08-12 CN claimed
EP-3609883-B1 FLUORINE-SUBSTITUTED INDAZOLE COMPOUNDS AND USES THEREOF SUNSHINE LAKE PHARMA CO LTD (CN) 2022-06-29 EP claimed
CN-114599653-A Indazoles as inhibitors of hematopoietic progenitor kinase 1(HPK1) and methods of use thereof 第一生物治疗股份有限公司 2022-06-07 CN claimed
CN-114599651-A Indazoles as inhibitors of hematopoietic progenitor kinase 1(HPK1) and methods of use thereof 第一生物治疗股份有限公司 2022-06-07 CN claimed
EP-0571822-B1 Diazabicycloalkene derivatives DAIICHI SEIYAKU CO (JP) 2001-08-16 EP claimed
WO-2000064927-A1 CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-11-02 WO claimed
EP-0882052-A1 NEW CEPHEM COMPOUNDS AND PHARMACEUTICAL USE THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1998-12-09 EP claimed
EP-0861249-A1 SUBSTITUTED SULFONYLALKANOYLAMINO HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1998-09-02 EP claimed
US-5753660-A Substituted sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors G. D. SEARLE & CO. (US) 1998-05-19 US claimed
WO-1997029111-A1 NEW CEPHEM COMPOUNDS AND PHARMACEUTICAL USE THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-08-14 WO claimed
WO-1997018205-A1 SUBSTITUTED SULFONYLALKANOYLAMINO HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1997-05-22 WO claimed
US-5418232-A Hypotensive, increases renal blood flow DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1995-05-23 US claimed
CN-1082547-A Azabicyclic compounds FUJISAWA PHARMACEUTICAL CO (JP) 1994-02-23 CN claimed
US-4966833-A USING HETEROCYCLIC NITROGEN CONTAINING COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1990-10-30 US claimed