Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | TACR2 | P21452 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SHBG | P04278 | 1/20 | 0.43 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11510673 | 1.00 | SKP2 (0.47) | SKP2HTR2ATLR8CYP3A4ALDH1A1 | |
| SCHEMBL5372549 | 0.98 | SKP2 (0.49) | SKP2HTR2ATLR8CYP3A4ALDH1A1 | |
| SCHEMBL8094486 | 0.95 | HTR2A (0.51) | SKP2HTR2ATLR8CYP3A4ALDH1A1 | |
| SCHEMBL8100500 | 0.95 | HTR2A (0.51) | SKP2HTR2ATLR8CYP3A4ALDH1A1 | |
| SCHEMBL8086520 | 0.95 | HTR2A (0.51) | SKP2HTR2ATLR8CYP3A4ALDH1A1 | |
| SCHEMBL8094156 | 0.95 | HTR2A (0.51) | SKP2HTR2ATLR8CYP3A4ALDH1A1 | |
| SCHEMBL8093788 | 0.95 | HTR2A (0.51) | SKP2HTR2ATLR8CYP3A4ALDH1A1 | |
| SCHEMBL8101948 | 0.95 | HTR2A (0.51) | SKP2HTR2ATLR8CYP3A4ALDH1A1 | |
| SCHEMBL8101711 | 0.95 | HTR2A (0.51) | SKP2HTR2ATLR8CYP3A4ALDH1A1 | |
| SCHEMBL8101341 | 0.95 | HTR2A (0.51) | SKP2HTR2ATLR8CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7202359-B2 | Azaoxa heterocyclic compound and method of preparing the same | CHANG CHUN PLASTICS CO., LTD. (TW) | 2007-04-10 | — | — | US | disclosed |
| US-20050085634-A1 | Azaoxa heterocyclic compound and method of preparing the same | CHANG CHUN PLASTICS CO., LTD. (TW) | 2005-04-21 | — | — | US | disclosed |
| US-20040068084-A1 | Azaoxa heterocyclic compound and method of preparing the same | CHANG CHUN PLASTICS CO., LTD. (TW) | 2004-04-08 | — | — | US | disclosed |
| US-4990586-A | Medical equipment | HEXCEL CORPORATION (US) | 1991-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040068084-A1 | Azaoxa heterocyclic compound and method of preparing the same | AOX1, KDM1A, BMI1 | SKP2 2214/4885HTR2A 2472/4885TLR8 4587/4885 |
| US-20050085634-A1 | Azaoxa heterocyclic compound and method of preparing the same | AOX1, KDM1A, BMI1 | SKP2 1761/4885HTR2A 2448/4885TLR8 4563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.