Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 16/20 | 0.66 |
| ▸ | MAOA | P21397 | 2/20 | 0.60 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26128487 | 0.85 | MAOB (0.60) | MAOBMAOAAPPGAAMAPT | |
| SCHEMBL7028448 | 0.84 | MAOB (0.67) | MAOBMAOAAPP | |
| SCHEMBL5089249 | 0.83 | MAOB (0.54) | MAOBMAOA | |
| SCHEMBL30792435 | 0.83 | MAOB (0.54) | MAOBMAOA | |
| SCHEMBL30792426 | 0.82 | MAOB (0.60) | MAOBMAOAAPPRAB9ASMN1; SMN2 | |
| SCHEMBL14541925 | 0.82 | MAOB (0.65) | MAOBMAOAAPPRAB9ASMN1; SMN2 | |
| SCHEMBL26127859 | 0.81 | MAOB (0.59) | MAOBMAOAAPPGAAMAPT | |
| SCHEMBL5121663 | 0.80 | MAOB (0.80) | MAOBMAOAAPPGAAMAPT | |
| SCHEMBL31542030 | 0.80 | MAOB (0.80) | MAOBMAOAAPPGAAMAPT | |
| SCHEMBL1578152 | 0.79 | MAOB (1.00) | MAOBMAOAAPPGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262318-B2 | Substituted heteroaryl- and phenylsulfamoyl compounds | PFIZER, INC. (US) | 2007-08-28 | — | — | US | disclosed |
| US-20060258723-A1 | Substituted Heteroaryl- and Phenylsulfamoyl Compounds | PFIZER INC | 2006-11-16 | — | — | US | disclosed |
| US-20050228015-A1 | Substituted heteroaryl- and phenylsulfamoyl compounds | PFIZER INC | 2005-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050228015-A1 | Substituted heteroaryl- and phenylsulfamoyl compounds | PPARA, PPARG, PPARD | MAOB 4263/4885MAOA 4248/4885APP 2597/4885 |
| US-20060258723-A1 | Substituted Heteroaryl- and Phenylsulfamoyl Compounds | PPARG, PPARA, PPARD | MAOB 4396/4885MAOA 4272/4885APP 3056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.